Mesencephalic astrocyte-derived neurotrophic factor (MANF) and cerebral dopamine
neurotrophic factor (CDNF) are endoplasmic reticulum (ER) luminal proteins that confer …

Stroke is a devastating medical condition with no treatment to hasten recovery. Its abrupt
nature results in cataclysmic changes in the affected tissues. Resident cells fail to cope with …

Ischaemic stroke remains a leading cause of disability and mortality worldwide and ageing-
associated inflammation for the aged patients specifically leads to worse post-stroke blood …

Ceramide, a bioactive sphingolipid, serves as an important second messenger in cell signal
transduction. Under stressful conditions, it can be generated from de novo synthesis …

The mesencephalic astrocyte‐derived neurotrophic factor (MANF), also named as arginine‐
rich protein (ARP) or arginine‐rich mutated in early‐stage tumors (ARMET), is a novel …

Pancreatitis and alcoholic pancreatitis are serious health concerns with an urgent need for
effective treatment strategies. Alcohol is a known etiological factor for pancreatitis, including …

Aims Mesencephalic astrocyte‐derived neurotrophic factor (MANF) is a secretory
neurotrophic factor protein that promotes repair after neuronal injury. The microglia cell …

Considerable efforts are currently made to develop strategies that boost endogenous
recovery once a stroke has occurred. Owing to their restorative properties, neurotrophic …

Synucleinopathies constitute a disease family named after alpha-synuclein protein, which is
a significant component of the intracellular inclusions called Lewy bodies. Accompanying …

Stroke has been associated with devastating clinical outcomes, with current treatment
strategies proving largely ineffective. Therefore, there is a need to explore alternative …