Osteoarthritis (OA) is a chronic degenerative joint disorder that leads to disability and affects
more than 500 million population worldwide. OA was believed to be caused by the wearing …

Rheumatoid arthritis (RA) is a systemic autoimmune disease that predominantly affects the
joints. The prevalence of RA varies globally, with generally a higher prevalence in …

Background Accurate data on type 1 diabetes prevalence, incidence, associated mortality
and life expectancy are crucial to inform public health policy, but these data are scarce. We …

Ageing organisms accumulate senescent cells that are thought to contribute to body
dysfunction. Telomere shortening and damage are recognized causes of cellular …

The therapeutic use of messenger RNA (mRNA) has fueled great hope to combat a wide
range of incurable diseases. Recent rapid advances in biotechnology and molecular …

Objective To report the global, regional, and national burden of chronic obstructive
pulmonary disease (COPD) and its attributable risk factors between 1990 and 2019, by age …

Depression rates in young people have risen sharply in the past decade, especially in
females, which is of concern because adolescence is a period of rapid social, emotional …

Objective Adolescence is a formative and turbulent phase where physiological,
psychosocial, and cognitive changes leave adolescents vulnerable to psychological …

Background: Preliminary data suggest that psilocybin-assisted treatment produces
substantial and rapid antidepressant effects in patients with major depressive disorder …

We provide quasi-experimental estimates of the impact of social media on mental health by
leveraging a unique natural experiment: the staggered introduction of Facebook across US …