Membrane targeting cationic antimicrobial peptides

D Ciumac, H Gong, X Hu, JR Lu - Journal of colloid and interface science, 2019 - Elsevier
Many short cationic peptides are amphiphilic and are often termed antimicrobial peptides
(AMPs) as they can kill various microorganisms. These AMPs have largely been discovered …

[HTML][HTML] Chemical modifications to increase the therapeutic potential of antimicrobial peptides

Y Han, M Zhang, R Lai, Z Zhang - Peptides, 2021 - Elsevier
The continued use of antibiotics has been accompanied by the rapid emergence and spread
of antibiotic-resistant strains of bacteria. Antimicrobial peptides (AMPs), also known as host …

Role of lipids in the interaction of antimicrobial peptides with membranes

V Teixeira, MJ Feio, M Bastos - Progress in lipid research, 2012 - Elsevier
Antimicrobial peptides (AMPs) take part in the immune system by mounting a first line of
defense against pathogens. Recurrent structural and functional aspects are observed …

Milk-derived antimicrobial peptides: overview, applications, and future perspectives

A Singh, RT Duche, AG Wandhare, JK Sian… - Probiotics and …, 2023 - Springer
The growing consumer awareness towards healthy and safe food has reformed food
processing strategies. Nowadays, food processors are aiming at natural, effective, safe, and …

Clinical application of AMPs

F Costa, C Teixeira, P Gomes, MCL Martins - … peptides: basics for clinical …, 2019 - Springer
Antimicrobial peptides (AMPs) have been described as one of the most promising
compounds able to address one of the main health threats of the twenty-first century that is …

S100 proteins as novel therapeutic targets in psoriasis and other autoimmune diseases

K Kurpet, G Chwatko - Molecules, 2022 - mdpi.com
Psoriasis is one of the most common inflammatory skin diseases affecting about 1–3% of the
population. One of the characteristic abnormalities in psoriasis is the excessive production of …

[HTML][HTML] Phospholipid dependent mechanism of smp24, an α-helical antimicrobial peptide from scorpion venom

PL Harrison, GR Heath, BRG Johnson… - … et Biophysica Acta (BBA …, 2016 - Elsevier
Determining the mechanism of action of antimicrobial peptides (AMPs) is critical if they are to
be developed into the clinical setting. In recent years high resolution techniques such as …

Unravelling a mechanism of action for a cecropin A-melittin hybrid antimicrobial peptide: the induced formation of multilamellar lipid stacks

T Silva, B Claro, BFB Silva, N Vale, P Gomes… - Langmuir, 2018 - ACS Publications
An understanding of the mechanism of action of antimicrobial peptides is fundamental to the
development of new and more active antibiotics. In the present work, we use a wide range of …

Macromolecular assembly and membrane activity of antimicrobial D, L-α-Cyclic peptides

B Claro, A Peon, E Gonzalez-Freire… - Colloids and Surfaces B …, 2021 - Elsevier
Antimicrobial peptides are viewed as a promising alternative to conventional antibiotics, as
their activity through membrane targeting makes them less prone to resistance development …

Antimicrobial peptides and their druggability, bio-safety, stability, and resistance

X Ma, R Aminov, OL Franco… - Frontiers in …, 2024 - frontiersin.org
The excessive and often indiscriminate use of antibiotics in many areas of human activities
has caused a widespread antibiotic resistance, which poses a major threat to the public …