In the era of organic synthesis, the direct difunctionalization strategies of alkenes and
alkynes are very eminent, which open up an excellent route to introduce two functional …

Compounds rich in sp3-hybridized carbons are desirable in drug discovery. Nickel-
catalyzed hydrocarbonation of alkenes is a potentially efficient method to synthesize these …

The cross-electrophile dialkylation of alkenes enables the formation of two C (sp3)–C (sp3)
bonds from readily available starting materials in a single transformation, thereby providing …

Carboxylation of easily available alkenes with CO2 is highly important to afford value‐added
carboxylic acids. Although dicarboxylation of activated alkenes, especially 1, 3‐dienes, has …

Conspectus Chain-walking offers extensive opportunities for innovating synthetic methods
that involve constructing chemical bonds at unconventional sites. This approach provides …

Three-component carboacylation of simple alkenes with readily available reagents is
challenging. Transition metal-catalysed intermolecular carboacylation works for alkenes with …

Regiodivergent alkene functionalization that produces either regioisomer starting from the
same raw materials is desirable. Herein, we report a nickel‐catalyzed switchable site …

The nickel-catalyzed multicomponent dicarbofunctionalization of alkenes represents one of
the most straightforward approaches to complex organofluorine compounds. However, the …

A Ni-catalyzed enantioselective reductive three-component alkylalkenylation of β, γ-alkenyl
ketones with cis-alkenyl iodides and fluoroalkyl iodides in the presence of Mn is reported. By …

Precisely introducing two similar functional groups into bulk chemical alkenes represents a
formidable route to complex molecules. Especially, the selective activation of two …