BACKGROUND: Worldwide, the Brugada syndrome has been recognized as an important
cause of sudden cardiac death in individuals at a relatively young age. Importantly, many …

Lithium is a commonly prescribed treatment for bipolar affective disorder. However,
treatment is complicated by lithium's narrow therapeutic index and the influence of kidney …

Lithium is widely used to treat bipolar disorder. Nephrogenic diabetes insipidus (NDI) is the
most common adverse effect of lithium and occurs in up to 40% of patients. Renal lithium …

First introduced as a new clinical entity in 1992, the Brugada syndrome is associated with a
relatively high risk of sudden death in young adults, and occasionally in children and infants …

Lithium has been used for the treatment of bipolar disorder for more than 6 decades.
Reports of cardiac side effects resulting in both benign electrocardiographic (ECG) changes …

Aims Fluctuations between the diagnostic ECG pattern and non-diagnostic ECGs in patients
with Brugada syndrome are known, but systematic studies are lacking. The purpose of this …

Prolongation of the QTc interval has been associated with proarrhythmia resulting from a
potentially fatal form of polymorphic ventricular tachycardia called torsades de pointes (TdP) …

Brugada syndrome is an inherited cardiac arrhythmia condition characterized by (i) coved
ST-elevation and J point elevation of at least 2 mm in at least two of the right precordial ECG …

A number of antipsychotic and antidepressant drugs are known to increase the risk of
ventricular arrhythmias and sudden cardiac death. Based largely on a concern over QT …

Neurological disorders including depression, anxiety, post-traumatic stress disorder (PTSD),
schizophrenia, autism and epilepsy are associated with an increased incidence of …