Effects of diet, lifestyle, chrononutrition and alternative dietary interventions on postprandial glycemia and insulin resistance

E Papakonstantinou, C Oikonomou, G Nychas… - Nutrients, 2022 - mdpi.com
As years progress, we are found more often in a postprandial than a postabsorptive state.
Chrononutrition is an integral part of metabolism, pancreatic function, and hormone …

Circadian rhythms and the molecular clock in cardiovascular biology and disease

S Crnko, BC Du Pré, JPG Sluijter… - Nature Reviews …, 2019 - nature.com
The Earth turns on its axis every 24 h; almost all life on the planet has a mechanism—
circadian rhythmicity—to anticipate the daily changes caused by this rotation. The molecular …

[HTML][HTML] Circadian modulation by time-restricted feeding rescues brain pathology and improves memory in mouse models of Alzheimer's disease

DS Whittaker, L Akhmetova, D Carlin, H Romero… - Cell metabolism, 2023 - cell.com
Circadian disruptions impact nearly all people with Alzheimer's disease (AD), emphasizing
both their potential role in pathology and the critical need to investigate the therapeutic …

Circadian rhythms, time-restricted feeding, and healthy aging

ENC Manoogian, S Panda - Ageing research reviews, 2017 - Elsevier
Circadian rhythms optimize physiology and health by temporally coordinating cellular
function, tissue function, and behavior. These endogenous rhythms dampen with age and …

Circadian disorganization alters intestinal microbiota

RM Voigt, CB Forsyth, SJ Green, E Mutlu, P Engen… - PloS one, 2014 - journals.plos.org
Intestinal dysbiosis and circadian rhythm disruption are associated with similar diseases
including obesity, metabolic syndrome, and inflammatory bowel disease. Despite the …

Mistimed sleep disrupts circadian regulation of the human transcriptome

SN Archer, EE Laing, CS Möller-Levet… - Proceedings of the …, 2014 - National Acad Sciences
Circadian organization of the mammalian transcriptome is achieved by rhythmic recruitment
of key modifiers of chromatin structure and transcriptional and translational processes …

Genome-wide and phase-specific DNA-binding rhythms of BMAL1 control circadian output functions in mouse liver

G Rey, F Cesbron, J Rougemont, H Reinke… - PLoS …, 2011 - journals.plos.org
The mammalian circadian clock uses interlocked negative feedback loops in which the
heterodimeric basic helix-loop-helix transcription factor BMAL1/CLOCK is a master …

Evolution of circadian rhythms: from bacteria to human

U Bhadra, N Thakkar, P Das, MP Bhadra - Sleep medicine, 2017 - Elsevier
The human body persists in its rhythm as per its initial time zone, and transition always occur
according to solar movements around the earth over 24 h. While traveling across different …

Crosstalk between the circadian clock circuitry and the immune system

N Cermakian, T Lange, D Golombek… - Chronobiology …, 2013 - Taylor & Francis
Various features, components, and functions of the immune system present daily variations.
Immunocompetent cell counts and cytokine levels present variations according to the time of …

Adverse childhood experiences predict the phenome of affective disorders and these effects are mediated by staging, neuroimmunotoxic and growth factor profiles

M Maes, M Rachayon, K Jirakran, P Sodsai… - Cells, 2022 - mdpi.com
Adverse childhood experiences (ACEs) enhance pro-inflammatory and pro-oxidant
responses. In affective disorders, recent precision nomothetic psychiatry studies disclosed …