Recent discoveries have led to the development of novel ideas and techniques that have
helped elucidate the correlation between epigenetics and tumor biology. Nowadays, the …

Early detection and characterization of molecular events associated with tumorgenesis
remain high priorities. Genome-wide epigenetic assays are promising diagnostic tools, as …

Improved risk stratification is needed for patients with localized prostate cancer. This study
characterized and assessed the prognostic potential of distinct immune cell infiltration …

Background Prognostic tools for prostate cancer (PC) are inadequate and new molecular
biomarkers may improve risk stratification. The epigenetic mark 5-hydroxymethylcytosine …

Aberrant methylation has been regarded as a hallmark of cancer. 5-hydroxymethylcytosine
(5hmC) is recently identified as the ten-eleven translocase (ten-eleven translocase) …

Purpose Methylation of 5th residue of cytosine in CpG island forms 5-methylcytosine which
is stable, heritable epigenetic mark. Methylation levels are broadly governed by …

Aims Fructose may play a crucial role in the pathogenesis of metabolic syndrome (MetS).
However, the pathogenic mechanism of the fructose-induced MetS has not yet been …

It has previously been shown that curcumin can effectively inhibit prostate cancer
proliferation and progression in TRAMP mice, potentially acting through the hypomethylation …

MiR-29b has been reported to be both a suppressor and a promoter in breast cancer (BC)
cells proliferation and metastasis. Significant efforts have been made to explain the …

Background Global DNA methylation alterations are hallmarks of cancer. The tumor-
suppressive TET enzymes, which are involved in DNA demethylation, are decreased in …