Nowadays we understand cell membranes not as a simple double lipid layer but as a
collection of complex and dynamic protein–lipid structures and microdomains that serve as …

Heat stress is a common and, therefore, an important environmental impact on cells and
organisms. While much attention has been paid to severe heat stress, moderate temperature …

Heat shock proteins (HSPs) are molecular chaperones facilitating the unfolding or folding of
secondary structures of proteins, their client proteins, in cellular stress situations. Various …

Reprogramming of gene expression is fundamental for skeletal muscle adaptations in
response to endurance exercise. This study investigated the time course-dependent …

During exercise, skeletal muscle produces reactive oxygen species (ROS) via NADPH
oxidase (NOX2) while inducing cellular adaptations associated with contractile activity. The …

The sarco/endoplasmic reticulum is an extensive, dynamic and heterogeneous
membranous network that fulfills multiple homeostatic functions. Among them, it …

Interleukin-6 (IL-6) is an important myokine that is highly expressed in skeletal muscle cells
upon exercise. We assessed IL-6 expression in response to electrical stimulation (ES) or …

Background Electrical activity regulates the expression of skeletal muscle genes by a
process known as “excitation-transcription”(ET) coupling. We have demonstrated that …

Dysferlin (DYSF) is involved in the membrane-repair process, in the intracellular vesicle
system and in T-tubule development in skeletal muscle. It interacts with mitsugumin 53 …

Skeletal muscle differentiation is a complex and highly regulated process characterized by
cell cycle arrest, which is associated with morphological changes including myoblast …