The global emergence of zoonotic viruses, including poxviruses, poses one of the greatest
threats to human and animal health. Forty years after the eradication of smallpox, emerging …

Poxviruses as a group can infect a large number of animals. However, at the level of
individual viruses, even closely related poxviruses display highly diverse host ranges and …

On May 8, 1980, the World Health Assembly at its 33rd session solemnly declared that the
world and all its peoples had won freedom from smallpox and recommended ceasing the …

The Poxviridae family is comprised of double-stranded DNA viruses belonging to
nucleocytoplasmic large DNA viruses (NCLDV). Among the NCLDV, poxviruses exhibit the …

This review provides a brief history of the impacts that a human-specific Orthopoxvirus
(OPXV), Variola virus, had on mankind, recalls how critical vaccination was for the …

A method of one-stage rapid identification of variola (VARV), monkeypox (MPXV), cowpox
(CPXV), and vaccinia (VACV) viruses, pathogenic for humans, utilizing multiplex real-time …

Monkeypox is a zoonotic disease endemic to central and western Africa, where it is a major
public health concern. Although Monkeypox virus (MPXV) and monkeypox disease in …

For almost 150 years after Edward Jenner had published the “Inquiry” in 1798, it was
generally assumed that the cowpox virus was the vaccine against smallpox. It was not until …

Background. Human infection by orthopoxviruses is being reported with increasing
frequency, attributed in part to the cessation of smallpox vaccination and concomitant …

The increasing frequency of monkeypox virus infections, new outbreaks of other zoonotic
orthopoxviruses and concern about the re-emergence of smallpox have prompted research …