Emerging hemostatic materials for non-compressible hemorrhage control

R Dong, H Zhang, B Guo - National Science Review, 2022 - academic.oup.com
Non-compressible hemorrhage control is a big challenge in both civilian life and the
battlefield, causing a majority of deaths among all traumatic injury mortalities. Unexpected …

Short peptide nanofiber biomaterials ameliorate local hemostatic capacity of surgical materials and intraoperative hemostatic applications in clinics

Z Yang, L Chen, J Liu, H Zhuang, W Lin… - Advanced …, 2023 - Wiley Online Library
Short designer self‐assembling peptide (dSAP) biomaterials are a new addition to the
hemostat group. It may provide a diverse and robust toolbox for surgeons to integrate wound …

Flexible bioactive glass nanofiber-based self-expanding cryogels with superelasticity and bioadhesion enabling hemostasis and wound healing

X Lu, Z Liu, Q Jia, Q Wang, Q Zhang, X Li, J Yu… - ACS nano, 2023 - ACS Publications
Self-expanding cryogels hold unique prospects for treating uncontrollable hemorrhages.
However, development of a mechanically robust, tissue-adhesive, and bioactive self …

Gelable and Adhesive Powder for Lethal Non‐Compressible Hemorrhage Control

K Zhang, Y Xian, M Li, Z Pan, Z Zhu… - Advanced Functional …, 2023 - Wiley Online Library
Hemostatic powders are widely used in clinical and emergency situations but often exhibit
low wet adhesion, cytotoxicity concerns, and do not work well for lethal non‐compressible …

Biomimetic and Multifunctional Hemostatic Hydrogel with Rapid Thermoresponsive Gelation and Robust Wet Adhesion for Emergency Hemostasis: A Rational Design …

H Song, L Xing, W Liu, X Wang, Z Hou… - …, 2023 - ACS Publications
Uncontrolled bleeding in emergency situations is a great threat to both military and civilian
lives, and an ideal hemostat for effectively controlling prehospital hemorrhage is urgently …

Naturally Derived Injectable Dual-Cross-Linked Adhesive Hydrogel for Acute Hemorrhage Control and Wound Healing

Z Zhu, H Ye, K Zhang, G He, Z Pan, Y Xian… - …, 2024 - ACS Publications
Developing biocompatible injectable hydrogels with high mechanical strength and rapid
strong tissue adhesion for hemostatic sealing of uncontrolled bleeding remains a prevailing …

Injectable Self‐Expanding/Self‐Propelling Hydrogel Adhesive with Procoagulant Activity and Rapid Gelation for Lethal Massive Hemorrhage Management

X Zhao, Y Huang, Z Li, J Chen, J Luo, L Bai… - Advanced …, 2024 - Wiley Online Library
Developing hydrogels that can quickly reach deep bleeding sites, adhere to wounds, and
expand to stop lethal and/or noncompressible bleeding in civil and battlefield environments …

Progress in injectable hydrogels for the treatment of incompressible bleeding: an update

X Wang, X Yang, Z Sun, X Guo, Y Teng… - … in Bioengineering and …, 2024 - frontiersin.org
Uncontrollable haemorrhage from deep, noncompressible wounds remains a persistent and
intractable challenge, accounting for a very high proportion of deaths in both war and …

A bibliometric analysis of publications on trauma-related hemorrhagic shock from 2012 to 2022: Research landscape and future trends

Z Du, T Wang - Medicine, 2023 - journals.lww.com
Trauma-related hemorrhagic shock is a global problem. This study aimed to analyze the
knowledge domain and frontiers of trauma-related hemorrhagic shock research through a …

Development of a national out-of-hospital transfusion protocol: a modified RAND Delphi study

J von Vopelius-Feldt, J Lockwood, S Mal… - … Open Access Journal, 2023 - cmajopen.ca
Background: Early resuscitation with blood components or products is emerging as best
practice in selected patients with trauma and medical patients; as a result, out-of-hospital …