Anthrax toxin

RJ Collier, JAT Young - Annual review of cell and …, 2003 - annualreviews.org
▪ Abstract Anthrax toxin consists of three nontoxic proteins that associate in binary or ternary
combinations to form toxic complexes at the surface of mammalian cells. One of these …

Disease detection and management via single nanopore-based sensors

JE Reiner, A Balijepalli, JWF Robertson… - Chemical …, 2012 - ACS Publications
As nanometer-scale portals in biological membranes, protein ionic channels act as
gatekeepers, controlling the traffic of ions and macromolecules into and out of cells …

Biology and taxonomy of Bacillus cereus, Bacillus anthracis, and Bacillus thuringiensis

GT Vilas-Bôas, APS Peruca… - Canadian journal of …, 2007 - cdnsciencepub.com
Three species of the Bacillus cereus group (Bacillus cereus, Bacillus anthracis, and Bacillus
thuringiensis) have a marked impact on human activity. Bacillus cereus and B. anthracis are …

Impairment of dendritic cells and adaptive immunity by anthrax lethal toxin

A Agrawal, J Lingappa, SH Leppla, S Agrawal… - Nature, 2003 - nature.com
Anthrax poses a clear and present danger as an agent of biological terrorism,,. Infection with
Bacillus anthracis, the causative agent of anthrax, if untreated can result in rampant …

[HTML][HTML] Anthrax toxin: a tripartite lethal combination

P Ascenzi, P Visca, G Ippolito, A Spallarossa… - FEBS letters, 2002 - Elsevier
Anthrax is a severe bacterial infection that occurs when Bacillus anthracis spores gain
access into the body and germinate in macrophages, causing septicemia and toxemia …

[HTML][HTML] NERVE: new enhanced reverse vaccinology environment

S Vivona, F Bernante, F Filippini - BMC biotechnology, 2006 - Springer
Background Since a milestone work on Neisseria meningitidis B, Reverse Vaccinology has
strongly enhanced the identification of vaccine candidates by replacing several …

Waning buoyancy in the crustal roots of old mountains

KM Fischer - Nature, 2002 - nature.com
When mountains form through the collision of lithospheric plates, uplift of the Earth's surface
is accompanied by thickening of the crust, and the buoyancy of these deep crustal roots …

Anthrax toxins and the host: a story of intimacy

M Mock, T Mignot - Cellular microbiology, 2003 - Wiley Online Library
Although the dramatic events of the year 2001 have revitalized the interest in anthrax,
research on Bacillus anthracis and its major virulence factors is one of the oldest theme in …

[HTML][HTML] Anthrax lethal factor proteolysis and inactivation of MAPK kinase

AP Chopra, SA Boone, X Liang… - Journal of Biological …, 2003 - ASBMB
Anthrax lethal toxin produced by the bacteriumBacillus anthracis is the major cause of death
in animals infected with anthrax. One component of this toxin, lethal factor (LF), inactivates …

Blocking anthrax lethal toxin at the protective antigen channel by using structure-inspired drug design

VA Karginov, EM Nestorovich… - Proceedings of the …, 2005 - National Acad Sciences
Bacillus anthracis secretes three polypeptides: protective antigen (PA), lethal factor (LF), and
edema factor (EF), which interact at the surface of mammalian cells to form toxic complexes …