It is now well established that the blood-clotting protein fibrinogen can polymerise into an
anomalous form of fibrin that is amyloid in character; the resultant clots and microclots entrap …

Parkinson's disease (PD) is a chronic, and highly neurodegenerative disorder with complex
pathological processes. The features for neuropathological identification of PD include α …

Misfolding and subsequent fibrillogenesis of α-synuclein (αSN) significantly influence the
development of Parkinson's disease (PD). This study reports the inhibitory effect of citrus …

Several studies have investigated if the levels of α-synuclein autoantibodies (α-syn AAb)
differ in serum of Parkinson's disease (PD) patients and healthy subjects. Reproducible …

Aims Accumulation and propagation of pathological α‐synuclein (α‐Syn) are the major
contributing factors to the pathogenesis of Parkinson's disease (PD). Therapy to halt the …

Background Presence of autoantibodies against α-synuclein (α-syn AAb) in serum of the
general population has been widely reported. That such peripheral factors may be involved …

Multiple-system trophy (MSA) and Parkinson's Disease (PD) are both progressive,
neurodegenerative diseases characterized by neuropathological deposition of aggregated …

B-1 cells have intricate biology, with distinct function, phenotype and developmental origin
from conventional B cells. They generate a B cell receptor with conserved germline …

Hereditary transthyretin (ATTRv) amyloidosis is a severe, progressive, and heterogeneous
multisystemic condition due to mutations in the TTR gene. Although multiple aspects of its …

The scope of the present review is to synthesize existing literature data on fluid biomarkers
for Parkinson's disease (PD) and atypical parkinsonian syndromes (APS). Parkinsonian …