Insights into the assembly and regulation of the bacterial divisome

TA Cameron, W Margolin - Nature Reviews Microbiology, 2024 - nature.com
The ability to split one cell into two is fundamental to all life, and many bacteria can
accomplish this feat several times per hour with high accuracy. Most bacteria call on an …

Splitsville: structural and functional insights into the dynamic bacterial Z ring

DP Haeusser, W Margolin - Nature Reviews Microbiology, 2016 - nature.com
Bacteria must divide to increase in number and colonize their niche. Binary fission is the
most widespread means of bacterial cell division, but even this relatively simple mechanism …

Protein sequence analysis using the MPI bioinformatics toolkit

F Gabler, SZ Nam, S Till, M Mirdita… - Current Protocols in …, 2020 - Wiley Online Library
Abstract The MPI Bioinformatics Toolkit (https://toolkit. tuebingen. mpg. de) provides
interactive access to a wide range of the best‐performing bioinformatics tools and …

Treadmilling by FtsZ filaments drives peptidoglycan synthesis and bacterial cell division

AW Bisson-Filho, YP Hsu, GR Squyres, E Kuru, F Wu… - Science, 2017 - science.org
The mechanism by which bacteria divide is not well understood. Cell division is mediated by
filaments of FtsZ and FtsA (FtsAZ) that recruit septal peptidoglycan-synthesizing enzymes to …

An ESCRT-III polymerization sequence drives membrane deformation and fission

AK Pfitzner, V Mercier, X Jiang, JM von Filseck, B Baum… - Cell, 2020 - cell.com
The endosomal sorting complex required for transport-III (ESCRT-III) catalyzes membrane
fission from within membrane necks, a process that is essential for many cellular functions …

The multicellular nature of filamentous heterocyst-forming cyanobacteria

A Herrero, J Stavans, E Flores - FEMS microbiology reviews, 2016 - academic.oup.com
Cyanobacteria carry out oxygenic photosynthesis, play a key role in the cycling of carbon
and nitrogen in the biosphere, and have had a large impact on the evolution of life and the …

Preparing samples from whole cells using focused-ion-beam milling for cryo-electron tomography

FR Wagner, R Watanabe, R Schampers, D Singh… - Nature protocols, 2020 - nature.com
Recent advances have made cryogenic (cryo) electron microscopy a key technique to
achieve near-atomic-resolution structures of biochemically isolated macromolecular …

MreB filaments align along greatest principal membrane curvature to orient cell wall synthesis

S Hussain, CN Wivagg, P Szwedziak, F Wong… - Elife, 2018 - elifesciences.org
MreB is essential for rod shape in many bacteria. Membrane-associated MreB filaments
move around the rod circumference, helping to insert cell wall in the radial direction to …

The hallmarks of living systems: towards creating artificial cells

NA Yewdall, AF Mason, JCM Van Hest - Interface Focus, 2018 - royalsocietypublishing.org
Despite the astonishing diversity and complexity of living systems, they all share five
common hallmarks: compartmentalization, growth and division, information processing …

FtsZ dynamics in bacterial division: What, how, and why?

JM Barrows, ED Goley - Current opinion in cell biology, 2021 - Elsevier
Bacterial cell division is orchestrated by the divisome, a protein complex centered on the
tubulin homolog FtsZ. FtsZ polymerizes into a dynamic ring that defines the division site …