Circadian rhythms, refractive development, and myopia

R Chakraborty, LA Ostrin, DL Nickla… - Ophthalmic and …, 2018 - Wiley Online Library
Purpose Despite extensive research, mechanisms regulating postnatal eye growth and
those responsible for ametropias are poorly understood. With the marked recent increases …

Allosteric modulators of metabotropic glutamate receptors as novel therapeutics for neuropsychiatric disease

DJ Luessen, PJ Conn - Pharmacological Reviews, 2022 - ASPET
Metabotropic glutamate (mGlu) receptors, a family of G-protein-coupled receptors, have
been identified as novel therapeutic targets based on extensive research supporting their …

Label-free highly multimodal nonlinear endoscope

D Septier, V Mytskaniuk, R Habert, D Labat… - Optics …, 2022 - opg.optica.org
We demonstrate a 2 mm diameter highly multimodal nonlinear micro-endoscope allowing
label-free imaging of biological tissues. The endoscope performs multiphoton fluorescence …

[HTML][HTML] Targeting mGluR group III for the treatment of neurodegenerative diseases

N Rabeh, B Hajjar, JO Maraka… - Biomedicine & …, 2023 - Elsevier
Glutamate, an excitatory neurotransmitter, is essential for neuronal function, and it acts on
ionotropic or metabotropic glutamate receptors (mGluRs). A disturbance in glutamatergic …

Full-field electroretinogram in autism spectrum disorder

PA Constable, SB Gaigg, DM Bowler, H Jägle… - Documenta …, 2016 - Springer
Purpose To explore early findings that individuals with autism spectrum disorder (ASD) have
reduced scotopic ERG b-wave amplitudes. Methods Light-adapted (LA) and dark-adapted …

mGlu receptors in the retina

A Dhingra, N Vardi - Wiley Interdisciplinary Reviews …, 2012 - Wiley Online Library
Glutamate, a key neurotransmitter in the vertebrate retina, acts via ionotropic and
metabotropic receptors. Retina expresses mRNA for all metabotropic glutamate receptors …

Phylogeny and expression divergence of metabotropic glutamate receptor genes in the brain of zebrafish (Danio rerio)

MF Haug, M Gesemann, T Mueller… - Journal of …, 2013 - Wiley Online Library
Glutamate, the most abundant excitatory neurotransmitter of the central nervous system,
modulates synaptic transmission and neuronal excitability via metabotropic glutamate …

Novel expression patterns of metabotropic glutamate receptor 6 in the zebrafish nervous system

YY Huang, MF Haug, M Gesemann, SCF Neuhauss - PloS one, 2012 - journals.plos.org
The metabotropic glutamate receptor 6 (mGluR6 or GRM6) belongs to the class III of the
metabotropic glutamate receptor family. It is the only known mGluR that mediates direct …

Homo-AMPA in the periaqueductal grey modulates pain and rostral ventromedial medulla activity in diabetic neuropathic mice

E Palazzo, S Boccella, I Marabese, M Perrone… - …, 2022 - Elsevier
Abstract The 2-amino-4-(3-hydroxy-5-methylisoxazol-4-yl)-butyric acid, homo-AMPA, an
analog of α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (AMPA) and 2 …

Metabotropic glutamate receptors and cognition: From underlying plasticity and neuroprotection to cognitive disorders and therapeutic targets

BK Hoglund, V Carfagno, MF Olive… - International Review of …, 2023 - Elsevier
Metabotropic glutamate (mGlu) receptors are G protein-coupled receptors that play pivotal
roles in mediating the activity of neurons and other cell types within the brain …