For decades, the use of secondary metabolites of various herbs has been an attractive
strategy in combating human diseases. Rosmarinic acid (RA) is a bioactive phenolic …

Depression and anxiety are the most prevalent neuropsychiatric disorders that have
emerged as global health concerns. Anxiolytic and antidepressant drugs, such as …

Given the stochastic complexity of cancer diseases, the development of chemotherapeutic
drugs is almost limited by problems of selectivity and side effects. Furthermore, an …

Ulcerative colitis (UC), a type of inflammatory bowel disease characterized by recurring and
incurable symptoms, causes immense suffering and economic burden for patients due to the …

Cancer constitutes a severe threat to human health and quality of life and is one of the most
significant causes of morbidity and mortality worldwide. Natural dietary products have drawn …

Phytochemicals are abundantly occurring natural compounds extracted from plant sources.
Rosmarinic acid (RA) is an abundant phytochemical of Lamiaceae species with various …

Background: Given the role of the P2X7 receptor (P2X7R) in inflammatory bowel diseases
(IBD), we investigated its role in the development and progression of colitis-associated …

Colorectal cancer (CRC) ranks as the third most aggressive tumor globally, and it can be
categorized into two forms: colitis-mediated CRC and sporadic CRC. The therapeutic …

Cancer is a global health challenge with high morbidity and mortality rates. However,
conventional cancer treatment methods often have severe side effects and limited success …

Colorectal cancer is a malignancy with high incidence and mortality worldwide, and
ulcerative colitis (UC) is strongly associated with colorectal cancer. Purple yam, also known …