Mammalian kidneys are specialized to maintain fluid and electrolyte homeostasis. The
epithelial transport processes along the renal tubule that match output to input have long …

Inhibitors of proximal tubular Na+-glucose cotransporter 2 (SGLT2) are natriuretic, and they
lower blood pressure. There are reports that the activities of SGLT2 and Na+-H+ exchanger …

Sex differences in renal electrolyte transport : Current Opinion in Nephrology and Hypertension
Sex differences in renal electrolyte transport : Current Opinion in Nephrology and Hypertension …

Compared with males, females have lower BP before age 60, blunted hypertensive
response to angiotensin II, and a leftward shift in pressure natriuresis. This study tested the …

Each day,~ 1.7 kg of NaCl and 180 liters of water are reabsorbed by nephron segments in
humans, with urinary excretion fine tuned to meet homeostatic requirements. These tasks …

Ca2+ transport along the nephron occurs via specific transcellular and paracellular
pathways and is coupled to the transport of other electrolytes. Notably, Na+ transport …

The goal of this study is to investigate the functional implications of the sexual dimorphism in
transporter patterns along the proximal tubule. To do so, we have developed sex-specific …

The goal of the present study was to investigate the functional implications of sexual
dimorphism in the pattern of transporters along the rodent nephron as reported by Veiras et …

The goal of this study was to investigate the functional implications of sex and species
differences in the pattern of transporters along nephrons in the rat and mouse kidney, as …

The kidneys maintain homeostasis by controlling the amount of water and electrolytes in the
blood. That function is accomplished by the nephrons, which transform glomerular filtrate …