Advanced analytical and informatic strategies for metabolite annotation in untargeted metabolomics
Liquid chromatography–mass spectrometry (LC–MS)-based untargeted metabolomics is
constantly challenged by large-scale and unambiguous metabolite annotation in complex …
constantly challenged by large-scale and unambiguous metabolite annotation in complex …
Enhancing capacity for food and nutrient intake assessment in population sciences research
ML Neuhouser, RL Prentice, LF Tinker… - Annual review of …, 2023 - annualreviews.org
Nutrition influences health throughout the life course. Good nutrition increases the
probability of good pregnancy outcomes, proper childhood development, and healthy aging …
probability of good pregnancy outcomes, proper childhood development, and healthy aging …
Metabolite annotation from knowns to unknowns through knowledge-guided multi-layer metabolic networking
Liquid chromatography-mass spectrometry (LC-MS) based untargeted metabolomics allows
to measure both known and unknown metabolites in the metabolome. However, unknown …
to measure both known and unknown metabolites in the metabolome. However, unknown …
Spatial metabolomics reveals skeletal myofiber subtypes
Skeletal muscle myofibers are heterogeneous in their metabolism. However, metabolomic
profiling of single myofibers has remained difficult. Mass spectrometry imaging (MSI) is a …
profiling of single myofibers has remained difficult. Mass spectrometry imaging (MSI) is a …
Tandem mass spectrometry molecular networking as a powerful and efficient tool for drug metabolism studies
Molecular networking (MN) has become a popular data analysis method for untargeted
mass spectrometry (MS)/MS-based metabolomics. Recently, MN has been suggested as a …
mass spectrometry (MS)/MS-based metabolomics. Recently, MN has been suggested as a …
An organ-specific metabolite annotation approach for ambient mass spectrometry imaging reveals spatial metabolic alterations of a whole mouse body
Y Zhu, Q Zang, Z Luo, J He, R Zhang… - Analytical …, 2022 - ACS Publications
Rapid and accurate metabolite annotation in mass spectrometry imaging (MSI) can improve
the efficiency of spatially resolved metabolomics studies and accelerate the discovery of …
the efficiency of spatially resolved metabolomics studies and accelerate the discovery of …
Metabolite fingerprinting of the ripening process in Pixian douban using a feature-based molecular network and metabolomics analysis
W Li, S Mei, H Zhou, MS Farid, T Hu, T Wu - Food Chemistry, 2023 - Elsevier
The unique flavor of Pixian douban (PXDB) is widely acknowledged to be associated with its
maturation process. However, there is limited knowledge about the non-volatile metabolites …
maturation process. However, there is limited knowledge about the non-volatile metabolites …
Expanding the scope of targeted metabolomics by one-pot microscale synthesis and tailored metabolite profiling: Investigation of bile acid–amino acid conjugates
Y Zhang, Y Huang, J Fan, M Zhang, A Hasan… - Analytical …, 2022 - ACS Publications
Accurate metabolite characterization plays a vital role in targeted metabolomics.
Nonetheless, the library of metabolites is still limited, especially for downstream conjugates …
Nonetheless, the library of metabolites is still limited, especially for downstream conjugates …
Evaluation of ion mobility spectrometry for improving constitutional assignment in natural product mixtures
The comprehensive chemical characterization of biological samples remains a central
challenge in the field of natural products. Conventional workflows using liquid …
challenge in the field of natural products. Conventional workflows using liquid …
Combining feature-based molecular networking and contextual mass spectral libraries to decipher nutrimetabolomics profiles
Untargeted metabolomics approaches deal with complex data hindering structural
information for the comprehensive analysis of unknown metabolite features. We investigated …
information for the comprehensive analysis of unknown metabolite features. We investigated …