During the past decade, mass spectrometry imaging (MSI) has become a robust and
versatile methodology to support modern pharmaceutical research and development. The …

Ambient mass spectrometry imaging (AMSI) is a molecular imaging technique developed in
recent years for in situ and real time visualization of the distribution of chemical compounds …

The recent upswing in the integration of spatial multi-omics for conducting multidimensional
information measurements is opening a new chapter in biological research. Mapping the …

Mass spectrometry imaging (MSI) is able to simultaneously record the distributions of
hundreds of molecules directly from tissue. Rapid direct tissue analysis is essential for MSI …

Here, we present native liquid extraction surface analysis (LESA) mass spectrometry
imaging of proteins and protein complexes from mouse brain and liver tissue. Intact proteins …

Safety issues caused by pharmaceuticals have frequently occurred worldwide, posing a
tremendous threat to human health. As an essential part of drug development, the …

Spatially targeted proteomics analyzes the proteome of specific cell types and functional
regions within tissue. While spatial context is often essential to understanding biological …

Matrix deposition plays an important role in obtaining high-quality and reliable molecular
spatial location information for matrix-assisted laser desorption/ionization mass spectrometry …

One critical aspect of mass spectrometry imaging (MSI) is the need to confidently identify
detected analytes. While orthogonal tandem MS (eg, LC–MS2) experiments from sample …

Ambient ionization methods have become important tools in mass spectrometry. The LMJ-
SSP can significantly simplify/reduce lengthy sample preparation requirements associated …