The quiet and underappreciated rise of drug-resistant invasive fungal pathogens
A Arastehfar, C Lass-Flörl, R Garcia-Rubio… - Journal of Fungi, 2020 - mdpi.com
Human fungal pathogens are attributable to a significant economic burden and mortality
worldwide. Antifungal treatments, although limited in number, play a pivotal role in …
worldwide. Antifungal treatments, although limited in number, play a pivotal role in …
The high osmolarity glycerol (HOG) pathway in fungi†
H Yaakoub, NS Sanchez, L Ongay-Larios… - Critical Reviews in …, 2022 - Taylor & Francis
While fungi are widely occupying nature, many species are responsible for devastating
mycosis in humans. Such niche diversity explains how quick fungal adaptation is necessary …
mycosis in humans. Such niche diversity explains how quick fungal adaptation is necessary …
Aspergillus fumigatus transcription factor ZfpA regulates hyphal development and alters susceptibility to antifungals and neutrophil killing during infection
TJ Schoen, DG Calise, JW Bok, MA Giese… - PLoS …, 2023 - journals.plos.org
Hyphal growth is essential for host colonization during Aspergillus infection. The
transcription factor ZfpA regulates A. fumigatus hyphal development including branching …
transcription factor ZfpA regulates A. fumigatus hyphal development including branching …
[HTML][HTML] The heat shock transcription factor HsfA is essential for thermotolerance and regulates cell wall integrity in Aspergillus fumigatus
JHTM Fabri, MC Rocha, CM Fernandes… - Frontiers in …, 2021 - frontiersin.org
The deleterious effects of human-induced climate change have long been predicted.
However, the imminent emergence and spread of new diseases, including fungal infections …
However, the imminent emergence and spread of new diseases, including fungal infections …
An oxylipin signal confers protection against antifungal echinocandins in pathogenic aspergilli
DG Calise, SC Park, JW Bok, GH Goldman… - Nature …, 2024 - nature.com
Aspergillus fumigatus is the leading causative agent of life-threatening invasive aspergillosis
in immunocompromised individuals. One antifungal class used to treat Aspergillus infections …
in immunocompromised individuals. One antifungal class used to treat Aspergillus infections …
Heterogeneity in the transcriptional response of the human pathogen Aspergillus fumigatus to the antifungal agent caspofungin
Aspergillus fumigatus is the main causative agent of invasive pulmonary aspergillosis (IPA),
a severe disease that affects immunosuppressed patients worldwide. The fungistatic drug …
a severe disease that affects immunosuppressed patients worldwide. The fungistatic drug …
Fungal tolerance to Congo red, a cell wall integrity stress, as a promising indicator of ecological niche
Differential sensitivities to the cell wall stress caused by Congo red (CR) have been
observed in many fungal species. In this study, the tolerances and sensitivities to CR was …
observed in many fungal species. In this study, the tolerances and sensitivities to CR was …
A Transient Receptor Potential-like Calcium Ion Channel in the Filamentous Fungus Aspergillus nidulans
H Wang, Q Chen, S Zhang, L Lu - Journal of Fungi, 2021 - mdpi.com
Transient Receptor Potential (TRP) proteins constitute a superfamily that encodes
transmembrane ion channels with highly diverse permeation and gating properties …
transmembrane ion channels with highly diverse permeation and gating properties …
Rapid automated antifungal susceptibility testing system for yeasts based on growth characteristics
J Yu, C He, T Wang, G Zhang, J Li, J Zhang… - Frontiers in Cellular …, 2023 - frontiersin.org
Fungal pathogens are a major threat to public health, as they are becoming increasingly
common and resistant to treatment, with only four classes of antifungal medicines currently …
common and resistant to treatment, with only four classes of antifungal medicines currently …
Induction of Aspergillus fumigatus zinc cluster transcription factor OdrA/Mdu2 provides combined cellular responses for oxidative stress protection and multiple …
C Sasse, E Bastakis, F Bakti, AM Höfer, I Zangl… - Mbio, 2023 - Am Soc Microbiol
ABSTRACT Z inc c luster transcription f actors (Zcfs) encoding zcf genes are exclusive for
fungi and required for multiple cellular processes including metabolism and development …
fungi and required for multiple cellular processes including metabolism and development …