Melanoma skin cancer is derived from skin melanocytes and has a high risk of metastatic
spread. Many clinical attributes and risk factors associated with melanoma have been well …

Melanoma cells can switch between a melanocytic and a mesenchymal-like state. Scattered
evidence indicates that additional intermediate state (s) may exist. Here, to search for such …

Melanoma, as a tumor cell derived from melanocyte transformation, has the characteristics
of malignant proliferation, high metastasis, rapid recurrence, and a low survival rate …

Melanoma is the deadliest skin cancer. Despite improvements in the understanding of the
molecular mechanisms underlying melanoma biology and in defining new curative …

Adjuvant systemic therapies are now routinely used following resection of stage III
melanoma, however accurate prognostic information is needed to better stratify patients. We …

Aims ATP-binding cassette (ABC) transporters constitute one of the largest families of
membrane proteins in most organisms; however, their functions in hepatocellular carcinoma …

Abstract Background Cutaneous Melanoma (CM) is a malignant disease with increasing
incidence and high mortality. Ferroptosis is a new kind of cell death and related to tumor …

In melanoma, predicting which tumors will ultimately metastasize guides treatment
decisions. Transcriptional signatures of primary tumors have been utilized to predict …

Simple Summary More than 40% of patients initially diagnosed with 'low risk'(stage I–II)
melanoma eventually develop melanoma recurrence or die as a result of melanoma. While …

Background Receptor tyrosine kinase-like orphan receptor 2 (ROR2) is a Wnt5a receptor
aberrantly expressed in cancer that was shown to either suppress or promote …