COVIDomics: The proteomic and metabolomic signatures of COVID-19
M Costanzo, M Caterino, R Fedele, A Cevenini… - International journal of …, 2022 - mdpi.com
Omics-based technologies have been largely adopted during this unprecedented global
COVID-19 pandemic, allowing the scientific community to perform research on a large scale …
COVID-19 pandemic, allowing the scientific community to perform research on a large scale …
Challenges in metabolomics-based tests, biomarkers revealed by metabolomic analysis, and the promise of the application of metabolomics in precision medicine
A Di Minno, M Gelzo, M Caterino, M Costanzo… - International Journal of …, 2022 - mdpi.com
Metabolomics helps identify metabolites to characterize/refine perturbations of biological
pathways in living organisms. Pre-analytical, analytical, and post-analytical limitations that …
pathways in living organisms. Pre-analytical, analytical, and post-analytical limitations that …
Dysregulation of lipid metabolism and pathological inflammation in patients with COVID-19
M Caterino, M Gelzo, S Sol, R Fedele, A Annunziata… - Scientific reports, 2021 - nature.com
In recent months, Coronavirus disease 2019 (COVID-19) caused by severe acute respiratory
syndrome coronavirus 2 (SARS-CoV-2) has spread throughout the world. COVID-19 …
syndrome coronavirus 2 (SARS-CoV-2) has spread throughout the world. COVID-19 …
The serum metabolome of moderate and severe COVID-19 patients reflects possible liver alterations involving carbon and nitrogen metabolism
M Caterino, M Costanzo, R Fedele, A Cevenini… - International journal of …, 2021 - mdpi.com
COVID-19 is a global threat that has spread since the end of 2019, causing severe clinical
sequelae and deaths, in the context of a world pandemic. The infection of the highly …
sequelae and deaths, in the context of a world pandemic. The infection of the highly …
Antioxidant and anti-aging activities of Laminaria japonica polysaccharide in Caenorhabditis elegans based on metabonomic analysis
N Li, Q Li, X He, X Gao, L Wu, M Xiao, W Cai… - International journal of …, 2022 - Elsevier
In this study, Laminaria japonica polysaccharide (LJP) was measured in vitro against three
antioxidant indicators: DPPH, ABTS, and hydroxyl. In vivo, LJP investigated thermal …
antioxidant indicators: DPPH, ABTS, and hydroxyl. In vivo, LJP investigated thermal …
Which role plays 2-hydroxybutyric acid on insulin resistance?
AP Sousa, DM Cunha, C Franco, C Teixeira, F Gojon… - Metabolites, 2021 - mdpi.com
Type 2 Diabetes Mellitus (T2D) is defined as a chronic condition caused by beta cell loss
and/or dysfunction and insulin resistance (IR). The discovering of novel biomarkers capable …
and/or dysfunction and insulin resistance (IR). The discovering of novel biomarkers capable …
Proteomics reveals that methylmalonyl-CoA mutase modulates cell architecture and increases susceptibility to stress
M Costanzo, M Caterino, A Cevenini, V Jung… - International journal of …, 2020 - mdpi.com
Methylmalonic acidemia (MMA) is a rare inborn error of metabolism caused by deficiency of
the methylmalonyl-CoA mutase (MUT) enzyme. Downstream MUT deficiency, methylmalonic …
the methylmalonyl-CoA mutase (MUT) enzyme. Downstream MUT deficiency, methylmalonic …
[HTML][HTML] GCIMS: An R package for untargeted gas chromatography–Ion mobility spectrometry data processing
S Oller-Moreno, C Mallafré-Muro, L Fernandez… - Chemometrics and …, 2023 - Elsevier
Abstract Gas-Chromatography coupled to Ion Mobility Spectrometry (GC-IMS) based
metabolomics is an emerging technique for obtaining fast, reliable untargeted metabolic …
metabolomics is an emerging technique for obtaining fast, reliable untargeted metabolic …
[HTML][HTML] A knock-in rat model unravels acute and chronic renal toxicity in glutaric aciduria type I
MG Melo, AO Fontana, D Viertl, G Allenbach… - Molecular Genetics and …, 2021 - Elsevier
Glutaric aciduria type I (GA-I, OMIM# 231670) is an autosomal recessive inborn error of
metabolism caused by deficiency of the mitochondrial enzyme glutaryl-CoA dehydrogenase …
metabolism caused by deficiency of the mitochondrial enzyme glutaryl-CoA dehydrogenase …
Metabolism of phenolics in coffee and plant-based foods by canonical pathways: an assessment of the role of fatty acid β-oxidation to generate biologically-active and …
MN Clifford, LJ King, A Kerimi… - Critical reviews in …, 2024 - Taylor & Francis
Abstract ω-Phenyl-alkenoic acids are abundant in coffee, fruits, and vegetables. Along with
ω-phenyl-alkanoic acids, they are produced from numerous dietary (poly) phenols and …
ω-phenyl-alkanoic acids, they are produced from numerous dietary (poly) phenols and …