[HTML][HTML] SOCS proteins in development and disease
MC Trengove, AC Ward - American journal of clinical and …, 2013 - ncbi.nlm.nih.gov
Cytokine and growth factor signaling mediates essential roles in the differentiation,
proliferation, survival and function of a number of cell lineages. This is achieved via specific …
proliferation, survival and function of a number of cell lineages. This is achieved via specific …
Myofibroblast differentiation and survival in fibrotic disease
K Kis, X Liu, JS Hagood - Expert reviews in molecular medicine, 2011 - cambridge.org
During wound healing, contractile fibroblasts called myofibroblasts regulate the formation
and contraction of granulation tissue; however, pathological and persistent myofibroblast …
and contraction of granulation tissue; however, pathological and persistent myofibroblast …
miR-150 promotes renal fibrosis in lupus nephritis by downregulating SOCS1
MicroRNAs (miRs) seem to mediate renal fibrosis in several renal diseases, with some miRs
having profibrotic effects and others having opposing effects. Although differential …
having profibrotic effects and others having opposing effects. Although differential …
Cerium oxide nanoparticle-induced pulmonary inflammation and alveolar macrophage functional change in rats
JY Ma, H Zhao, RR Mercer, M Barger, M Rao… - …, 2011 - Taylor & Francis
The use of cerium compounds as diesel fuel catalyst results in the emission of cerium oxide
nanoparticles (CeO2) in the exhaust. This study characterized the potential effects of CeO2 …
nanoparticles (CeO2) in the exhaust. This study characterized the potential effects of CeO2 …
Pulmonary microRNA profiling in a mouse model of ventilator-induced lung injury
K Vaporidi, E Vergadi, E Kaniaris… - … of Physiology-Lung …, 2012 - journals.physiology.org
The aim of this study was to investigate the changes induced by high tidal volume ventilation
(HVTV) in pulmonary expression of micro-RNAs (miRNAs) and identify potential target …
(HVTV) in pulmonary expression of micro-RNAs (miRNAs) and identify potential target …
Suppressor of cytokine signalling (SOCS) proteins as guardians of inflammatory responses critical for regulating insulin sensitivity
S Galic, N Sachithanandan, TW Kay… - Biochemical …, 2014 - portlandpress.com
Overactivation of immune pathways in obesity is an important cause of insulin resistance
and thus new approaches aimed to limit inflammation or its consequences may be effective …
and thus new approaches aimed to limit inflammation or its consequences may be effective …
Macrophage micro-RNA-155 promotes lipopolysaccharide-induced acute lung injury in mice and rats
W Wang, Z Liu, J Su, WS Chen… - … of Physiology-Lung …, 2016 - journals.physiology.org
Micro-RNA (miR)-155 is a novel gene regulator with important roles in inflammation. Herein,
our study aimed to explore the role of miR-155 in LPS-induced acute lung injury (ALI). ALI in …
our study aimed to explore the role of miR-155 in LPS-induced acute lung injury (ALI). ALI in …
Reversal of the Transcriptome by Prostaglandin E2 during Myofibroblast Dedifferentiation
SH Wettlaufer, JP Scott, RC McEachin… - American journal of …, 2016 - atsjournals.org
Myofibroblasts, the major effector cells in pathologic fibrosis, derive from the differentiation of
fibroblasts driven by mediators such as transforming growth factor-β1 (TGF-β1) and …
fibroblasts driven by mediators such as transforming growth factor-β1 (TGF-β1) and …
Co-delivery of dexamethasone and a microRNA-155 inhibitor using dendrimer-entrapped gold nanoparticles for acute lung injury therapy
C Li, J Li, Y Fan, D Wang, M Zhan, M Shen… - …, 2021 - ACS Publications
Development of nanomedicines for effective therapy of acute lung injury (ALI), a common
critical respiratory failure syndrome, remains to be challenging. We report here a unique …
critical respiratory failure syndrome, remains to be challenging. We report here a unique …
Heterogeneity in fibroblast proliferation and survival in idiopathic pulmonary fibrosis
DM Habiel, C Hogaboam - Frontiers in pharmacology, 2014 - frontiersin.org
Idiopathic pulmonary fibrosis (IPF) is the most common form of interstitial lung disease
characterized by the persistence of activated myofibroblasts resulting in excessive …
characterized by the persistence of activated myofibroblasts resulting in excessive …