Cytokine and growth factor signaling mediates essential roles in the differentiation,
proliferation, survival and function of a number of cell lineages. This is achieved via specific …

During wound healing, contractile fibroblasts called myofibroblasts regulate the formation
and contraction of granulation tissue; however, pathological and persistent myofibroblast …

MicroRNAs (miRs) seem to mediate renal fibrosis in several renal diseases, with some miRs
having profibrotic effects and others having opposing effects. Although differential …

The use of cerium compounds as diesel fuel catalyst results in the emission of cerium oxide
nanoparticles (CeO2) in the exhaust. This study characterized the potential effects of CeO2 …

The aim of this study was to investigate the changes induced by high tidal volume ventilation
(HVTV) in pulmonary expression of micro-RNAs (miRNAs) and identify potential target …

Overactivation of immune pathways in obesity is an important cause of insulin resistance
and thus new approaches aimed to limit inflammation or its consequences may be effective …

Micro-RNA (miR)-155 is a novel gene regulator with important roles in inflammation. Herein,
our study aimed to explore the role of miR-155 in LPS-induced acute lung injury (ALI). ALI in …

Myofibroblasts, the major effector cells in pathologic fibrosis, derive from the differentiation of
fibroblasts driven by mediators such as transforming growth factor-β1 (TGF-β1) and …

Development of nanomedicines for effective therapy of acute lung injury (ALI), a common
critical respiratory failure syndrome, remains to be challenging. We report here a unique …

Idiopathic pulmonary fibrosis (IPF) is the most common form of interstitial lung disease
characterized by the persistence of activated myofibroblasts resulting in excessive …