RNA modifications have become hot topics recently. By influencing RNA processes,
including generation, transportation, function, and metabolization, they act as critical …

Currently, more than 170 modifications have been identified on RNA. Among these RNA
modifications, various methylations account for two-thirds of total cases and exist on almost …

Cancer is one of the major diseases threatening human life and health worldwide.
Epigenetic modification refers to heritable changes in the genetic material without any …

Epigenetic modification plays a crucial regulatory role in the biological processes of
eukaryotic cells. The recent characterization of DNA and RNA methylation is still ongoing …

The development of next-generation sequencing technology and the discovery of specific
antibodies targeting chemically modified nucleotides have paved the way for a new era of …

Specific RNA sequences modified by a methylated adenosine, N 6-methyladenosine (m 6
A), contribute to the post-transcriptional regulation of gene expression. The quantity of m 6 A …

Epigenetic regulation involves a range of sophisticated processes which contribute to
heritable alterations in gene expression without altering DNA sequence. Regulatory events …

Summary N 6-Methyladenosine (m 6 A), the most abundant internal mRNA modification,
affects multiple steps in gene expression. Mechanistically, the binding of YTHDF2 to m 6 A …

Abstract N6-methyladenosine (m6A) modification is a dynamic and reversible post-
transcriptional modification and the most prevalent internal RNA modification in eukaryotic …

Biomolecular condensates are membraneless organelles (MLOs) that form dynamic,
chemically distinct subcellular compartments organizing macromolecules such as proteins …