Colonization of the human stomach by Helicobacter pylori and its role in causing gastric
cancer is one of the richest examples of a complex relationship among human cells …

Chronic infection with Helicobacter pylori cagA-positive strains is the strongest risk factor for
gastric cancer. The cagA gene product, CagA, is delivered into gastric epithelial cells via the …

Helicobacter pylori is a gastric pathogen that colonizes approximately 50% of the world's
population. Infection with H. pylori causes chronic inflammation and significantly increases …

Chronic infection with Helicobacter pylori cagA-positive strains is the strongest risk factor of
gastric cancer. The cagA gene-encoded CagA protein is delivered into gastric epithelial …

Helicobacter pylori is the first formally recognized bacterial carcinogen and is one of the
most successful human pathogens, as over half of the world's population is colonized with …

Although gastric adenocarcinoma is associated with the presence of Helicobacter pylori in
the stomach, only a small fraction of colonized individuals develop this common malignancy …

In this review, we focus on a group of mobile genetic elements designated pathogenicity
islands (PAI). These elements play a pivotal role in the virulence of bacterial pathogens of …

Helicobacter pylori CagA protein is associated with severe gastritis and gastric carcinoma.
CagA is injected from the attached Helicobacter pylori into host cells and undergoes tyrosine …

Helicobacter pylori are spiral-shaped gram-negative bacteria with polar flagella that live
near the surface of the human gastric mucosa. They have evolved intricate mechanisms to …

More than 50% of the world's population is infected with Helicobacter pylori (H. pylori).
Chronic infection with this Gram-negative pathogen is associated with the development of …