Evidence-based use of levothyroxine/liothyronine combinations in treating hypothyroidism: a consensus document

J Jonklaas, AC Bianco, AR Cappola… - European thyroid …, 2021 - etj.bioscientifica.com
Background: Fourteen clinical trials have not shown a consistent benefit of combination
therapy with levothyroxine (LT4) and liothyronine (LT3). Despite the publication of these …

Optimal thyroid hormone replacement

J Jonklaas - Endocrine reviews, 2022 - academic.oup.com
Hypothyroidism is a common endocrinopathy, and levothyroxine is frequently prescribed.
Despite the basic tenets of initiating and adjusting levothyroxine being agreed on, there are …

The enigma of persistent symptoms in hypothyroid patients treated with levothyroxine: A narrative review

P Perros, C Van Der Feltz‐Cornelis… - Clinical …, 2023 - Wiley Online Library
A significant minority of patients with hypothyroidism report persistent symptoms despite
achieving normal thyroid biochemistry after levothyroxine (L‐T4) replacement. Four principal …

Brain fog in hypothyroidism: what is it, how is it measured, and what can be done about it

MH Samuels, LJ Bernstein - Thyroid, 2022 - liebertpub.com
Background: Some levothyroxine (LT4)-treated hypothyroid patients report a constellation of
persistent and distressing cognitive symptoms that has been termed brain fog. This narrative …

Use of liothyronine (T3) in hypothyroidism: Joint British Thyroid Association/Society for endocrinology consensus statement

R Ahluwalia, SE Baldeweg, K Boelaert… - Clinical …, 2023 - Wiley Online Library
Persistent symptoms in patients treated for hypothyroidism are common. Despite more than
20 years of debate, the use of liothyronine for this indication remains controversial, as …

The impact of hypothyroidism on satisfaction with care and treatment and everyday living: results from E-mode patient self-assessment of thyroid therapy, a cross …

P Perros, L Hegedüs, EV Nagy, E Papini, HA Hay… - Thyroid, 2022 - liebertpub.com
Background: Hypothyroid patients often report dissatisfaction and poor quality of life. This
survey explored the impact of hypothyroidism on patient satisfaction, everyday living …

What is the quality of life in patients treated with levothyroxine for hypothyroidism and how are we measuring it? A critical, Narrative review

F Borson-Chazot, JL Terra, B Goichot… - Journal of Clinical …, 2021 - mdpi.com
Thyroid hormone replacement therapy (THRT, generally using oral levothyroxine (LT4)) is a
safe, effective means of treating hypothyroidism. However, a proportion of LT4-treated …

Lifestyle is associated with thyroid function in subclinical hypothyroidism: a cross-sectional study

K Wu, Y Zhou, S Ke, J Huang, X Gao, B Li, X Lin… - BMC endocrine …, 2021 - Springer
Background Few studies have focused on the association between lifestyle and subclinical
hypothyroidism (SCH). The purpose of this study was to investigate the association between …

Effects of aerobic, resistance, and combined training on thyroid function and quality of life in hypothyroidism. A randomized controlled trial

AM Ahmad, ZH Serry, HA Abd Elghaffar… - … Therapies in Clinical …, 2023 - Elsevier
Purpose This study aimed to compare the effects of aerobic, resistance, and combined
exercises on thyroid function, lipid profile, exercise capacity, and quality of life (QoL) in …

Lifestyle and Quality of Life of Women with Diagnosed Hypothyroidism in the Context of Metabolic Disorders

B Janota, E Szczepańska, K Noras, E Janczewska - Metabolites, 2023 - mdpi.com
The lifestyle causes of metabolic disorders in patients with hypothyroidism should be
investigated. We aimed to assess the lifestyle and quality of life of women diagnosed with …