Chemotherapeutic potential of betanin/capecitabine combination targeting colon cancer: experimental and bioinformatic studies exploring NFκB and cyclin D1 …

R Ahmed, SA Zaitone, AKK Abdelmaogood… - Frontiers in …, 2024 - frontiersin.org
Introduction: Betanin (C₂₄H₂₆N₂O₁₃) is safe to use as food additives approved by the
FDA with anti-inflammatory and anticancer effects in many types of cancer cell lines. The …

Protection of Proanthocyanidins Against HSP Serum-Induced Inflammation and Oxidative Stress on Human Umbilical Vein Endothelial Cells

L Liu, M Wang, M Guo, L Xian, J Xu… - Clinical, Cosmetic and …, 2024 - Taylor & Francis
Background Immune-mediated inflammation and oxidative stress play pivotal roles in
Henoch-Schonlein purpura (HSP), primarily through the TLR4/MyD88/NF-κB pathway …

Co-culturing of Saccharomycopsis fibuligera and Lacticaseibacillus paracasei to improve the bioactive components and flavor characteristics of Dendrobium officinale

L Xiaoye, W Liu, W Huang, X Wang, L Li, X Zhao, S Qiu - Food Bioscience, 2024 - Elsevier
In this study, Saccharomycopsis fibuligera FBKL2. 8DCJS1 and Lacticaseibacillus paracasei
FBKL1. 3028 were jointly introduced into Dendrobium officinale liquid to probe alterations in …

Computational and Experimental Approaches Exploring the Role of Hesperetin in Improving Autophagy in Rat Diabetic Retinopathy

R Alshaman, E Kolieb, RM El-Sayed, SG Gouda… - Biomedicines, 2024 - mdpi.com
Diabetic retinopathy (DR) is a debilitating diabetic disorder of the retinal microvasculature
and the main cause of avoidable blindness in old people. Hesperetin is a plant flavanone …

miR-26a improves microglial activation and neuronal apoptosis in a rat model of cerebral infarction by regulating the TREM1-TLR4/MyD88/NF-κB axis.

D Xu, Q Guo - Developmental Neuroscience, 2023 - karger.com
Emerging studies have indicated that abnormally expressed microRNAs (miRNAs) are
related to the pathogenesis of cerebral ischemia. Nevertheless, the function of miR-26a in …