In recent years, neutrophils have attracted increasing attention because of their cancer-
promoting effects. An elevated neutrophil-to-lymphocyte ratio is considered a prognostic …

Colorectal cancer (CRC) is often associated with metastasis and recurrence and is the
leading cause of cancer-related mortality. In the progression of CRC, recent studies have …

Reprogramming somatic cells into megakaryocytes (MKs) would provide a promising source
of platelets. However, using a pharmacological approach to generate human MKs from …

Neural progenitor cells (NPCs) capable of self-renewal and differentiation into neural cell
lineages offer broad prospe ts for cell therapy for neurodegenerative diseases. However …

Parkinson's disease (PD) is a progressive neurodegenerative movement disorder of the
central nervous system that results from the loss of dopaminergic (DA) nigral neurons …

Immunotherapy, particularly immune checkpoint blockade (ICB), has shown great promise in
the treatment of cancer and emerged as a beacon of hope for patients who have exhausted …

Background Platelet transfusion therapy has made a great breakthrough in clinical practice,
and the differentiation of human embryonic stem cells (hESCs) to produce functional …

Hematopoietic stem cell (HSC) transplantation is used to treat blood and immunodeficient
diseases. HSC expansion techniques must be developed to prevent complications and …

The technique of induced pluripotent stem cells has significant application value in breeding
and preserving the genetic integrity of fish species. However, it is still unclear whether the …

Xylene exposure is known to induce toxicity in hematopoietic stem and progenitor cells
(HSPCs), leading to bone marrow suppression and potential leukemogenesis. However …