Astrocytes are neural cells of ectodermal, neuroepithelial origin that provide for homeostasis
and defense of the central nervous system (CNS). Astrocytes are highly heterogeneous in …

Astrocytes are the predominant cell type in the brain and perform key functions vital to CNS
physiology, including blood brain barrier formation and maintenance, synaptogenesis …

Oligodendrocytes, the myelin-forming cells of the central nervous system (CNS), and
astrocytes constitute macroglia. This review deals with the recent progress related to the …

Drosophila neuroblasts, the stem cells of the developing fly brain, have emerged as a key
model system for neural stem cell biology and have provided key insights into the …

The nematode Caenorhabditis elegans is a powerful experimental setting for uncovering
fundamental tenets of nervous system organization and function. Its nearly invariant and …

Trophoblasts, the specialized cells of the placenta, play a major role in implantation and
formation of the maternal-fetal interface. Through an unusual differentiation process …

Multipotent stem cells that generate both neurons and glia are widespread components of
the early neuroepithelium. During CNS development, neurogenesis largely precedes …

Glial cells constitute without any dispute an essential element in providing an efficiently
operating nervous system. Work in many labs over the last decades has demonstrated that …

During development, basic helix–loop–helix (bHLH) proteins regulate formation of neurons
from multipotent progenitor cells. However, bHLH factors linked to gliogenesis have not …

▪ Abstract The Notch signaling pathway has long been known to influence cell fate in the
developing nervous system. However, this pathway has generally been thought to inhibit the …