Piezoelectric biomaterials inspired by nature for applications in biomedicine and nanotechnology

S Chen, X Tong, Y Huo, S Liu, Y Yin, ML Tan… - Advanced …, 2024 - Wiley Online Library
Bioelectricity provides electrostimulation to regulate cell/tissue behaviors and functions. In
the human body, bioelectricity can be generated in electromechanically responsive tissues …

Electrical fields in wound healing—an overriding signal that directs cell migration

M Zhao - Seminars in cell & developmental biology, 2009 - Elsevier
Injury that disrupts an epithelial layer instantaneously generates endogenous electric fields
(EFs), which were detected at human skin wounds over 150 years ago. Recent researches …

A link between tear instability and hyperosmolarity in dry eye

H Liu, C Begley, M Chen, A Bradley… - … & visual science, 2009 - iovs.arvojournals.org
purpose. Tear film instability and tear hyperosmolarity are considered core mechanisms in
the development of dry eye. The authors hypothesize that evaporation and instability …

A Self-Powered Hydrogel/Nanogenerator System Accelerates Wound Healing by Electricity-Triggered On-Demand Phosphatase and Tensin Homologue (PTEN) …

S Fu, S Yi, Q Ke, K Liu, H Xu - ACS nano, 2023 - ACS Publications
Electrical stimulation therapy (EST) has been established as an effective strategy to
accelerate wound healing by stimulating cell proliferation and migration, ultimately …

Mouse models of cystic fibrosis: phenotypic analysis and research applications

M Wilke, RM Buijs-Offerman, J Aarbiou… - Journal of Cystic …, 2011 - Elsevier
Genetically modified mice have been studied for more than fifteen years as models of cystic
fibrosis (CF). The large amount of experimental data generated illuminates the complex …

Dynamics and function of the tear film in relation to the blink cycle

RJ Braun, PE King-Smith, CG Begley, L Li… - Progress in retinal and …, 2015 - Elsevier
Great strides have recently been made in quantitative measurements of tear film thickness
and thinning, mathematical modeling thereof and linking these to sensory perception. This …

[PDF][PDF] Directed migration of human bone marrow mesenchymal stem cells in a physiological direct current electric field

Z Zhao, C Watt, A Karystinou, AJ Roelofs… - Eur Cell …, 2011 - researchgate.net
At sites of bone fracture, naturally-occurring electric fields (EFs) exist during healing and
may guide cell migration. In this study, we investigated whether EFs could direct the …

Wireless‐powered electrical bandage contact lens for facilitating corneal wound healing

Q Wu, C Yang, W Chen, K Chen, H Chen… - Advanced …, 2022 - Wiley Online Library
Corneal injury can lead to severe vision impairment or even blindness. Although numerous
methods are developed to accelerate corneal wound healing, most of them are passive …

Mechanistic modeling of ophthalmic drug delivery to the anterior chamber by eye drops and contact lenses

S Gause, KH Hsu, C Shafor, P Dixon, KC Powell… - Advances in colloid and …, 2016 - Elsevier
Ophthalmic drug for the anterior chamber diseases are delivered into tears by either eye
drops or by extended release devices placed in the eyes. The instilled drug exits the eye …

Experimental pharmacotherapy for dry eye disease: a review

M Baiula, S Spampinato - Journal of experimental pharmacology, 2021 - Taylor & Francis
Dry eye disease (DED) is a complex multifactorial disease showing heterogenous
symptoms, including dryness, photophobia, ocular discomfort, irritation and burning but also …