The human eye is a complex organ consisting of multiple compartments with unique and
specialized properties that reflect their varied functions. Although there have been …

Human macrophage migration inhibition factor (MIF) is a protein with cytokine and
chemokine properties that regulates a diverse range of physiological functions related to …

Aldehyde oxidase (AOX) is a cytosolic drug-metabolizing enzyme which has attracted
increasing attention in drug development due to its high hepatic expression, broad substrate …

Emerging fungal diseases have become challenges for wildlife health and conservation.
North American hibernating bat species are threatened by the psychrophilic fungus …

Search for ideal compounds with known pathways of anticancer mechanism is still a priority
research focus for cancer, as it continues to be a major health challenge across the globe …

Vision is necessary for a healthy and independentlife. Globally, about 2.2 billionindividuals
suffer from eye diseasesthat lead to visual impairment or blindness (WHO 2019), thus …

Purpose Diverse groups of proteins play integral roles in both the physiology and
pathophysiology of the retina. However, thorough proteomic analyses of retinas of …

Alpha-2-macroglobulin (A2M) is a protease inhibitor that regulates extracellular matrix
(ECM) stability and turnover. Here, we show that A2M is expressed by endothelial cells …

The importance of olfaction to human health and disease is often underappreciated.
Olfactory dysfunction has been reported in association with a host of common complex …

Eye disorders and resulting visual loss are major public health problems affecting millions of
people worldwide. In this context, the sclera is an opaque, thick outer coat covering more …