Interpreting stress responses during routine toxicity studies: a review of the biology, impact, and assessment

NE Everds, PW Snyder, KL Bailey… - Toxicologic …, 2013 - journals.sagepub.com
Stress often occurs during toxicity studies. The perception of sensory stimuli as stressful
primarily results in catecholamine release and activation of the hypothalamic–pituitary …

Emotional stress and cardiovascular complications in animal models: a review of the influence of stress type

CC Crestani - Frontiers in physiology, 2016 - frontiersin.org
Emotional stress has been recognized as a modifiable risk factor for cardiovascular
diseases. The impact of stress on physiological and psychological processes is determined …

T lymphocytes and vascular inflammation contribute to stress-dependent hypertension

PJ Marvar, A Vinh, S Thabet, HE Lob, D Geem… - Biological …, 2012 - Elsevier
BACKGROUND: Psychological stress is a significant risk factor for hypertension and also
directly affects the immune system. We have previously reported that T lymphocytes are …

[PDF][PDF] Neuroendocrine profiling in inherited stress-induced arterial hypertension rat strain with stress-sensitive arterial hypertension

AL Markel, OE Redina, MA Gilinsky, GM Dymshits… - Journal of …, 2007 - Citeseer
The functions of the hypothalamic adrenal cortical and sympathetic adrenal medullary
systems were studied in rats with inherited stress-induced arterial hypertension (ISIAH …

Global disturbances in autonomic function yield cardiovascular instability and hypertension in the chromogranin a null mouse

JR Gayen, Y Gu, DT O'Connor, SK Mahata - Endocrinology, 2009 - academic.oup.com
We reported previously that chromogranin A (Chga) knockout (KO) mice are hypertensive
and hyperadrenergic. Here we sought to determine the basis of such alterations by probing …

Role of the autonomic nervous system and baroreflex in stress-evoked cardiovascular responses in rats

DG Dos Reis, EAT Fortaleza, RF Tavares, FMA Corrêa - Stress, 2014 - Taylor & Francis
Restraint stress (RS) is an experimental model to study stress-related cardiovascular
responses, characterized by sustained pressor and tachycardiac responses. We used …

Acute restraint stress induces endothelial dysfunction: role of vasoconstrictor prostanoids and oxidative stress

APP Carda, KC Marchi, E Rizzi, AS Mecawi… - Stress, 2015 - Taylor & Francis
We hypothesized that acute stress would induce endothelial dysfunction. Male Wistar rats
were restrained for 2 h within wire mesh. Functional and biochemical analyses were …

Effect of acute restraint stress on the tachycardiac and bradycardiac responses of the baroreflex in rats

CC Crestani, RF Tavares, FHF Alves, LBM Resstel… - Stress, 2010 - Taylor & Francis
In the present study, we evaluated cardiac baroreflex responses of rats submitted to acute
restraint stress. The baroreflex was tested: immediately before, during a 30 min exposure to …

Hedgehog signalling in endocrine development and disease

PJ King, L Guasti, E Laufer - Journal of Endocrinology, 2008 - joe.bioscientifica.com
The present study aimed to examine whether transplacental exposure to progesterone
caused male reproductive abnormalities and whether the changes can be reversed after …

Nesfatin‐1 activates cardiac vagal neurons of nucleus ambiguus and elicits bradycardia in conscious rats

GC Brailoiu, E Deliu, AA Tica… - Journal of …, 2013 - Wiley Online Library
Nesfatin‐1, a peptide whose receptor is yet to be identified, has been involved in the
modulation of feeding, stress, and metabolic responses. More recently, increasing evidence …