Biosystem‐inspired engineering of nanozymes for biomedical applications

L Zhang, H Wang, X Qu - Advanced Materials, 2024 - Wiley Online Library
Nanozymes with intrinsic enzyme‐mimicking activities have shown great potential to
become surrogates of natural enzymes in many fields by virtue of their advantages of high …

Current Advances on the Single‐Atom Nanozyme and Its Bioapplications

C Peng, R Pang, J Li, E Wang - Advanced Materials, 2024 - Wiley Online Library
Nanozymes, a class of nanomaterials mimicking the function of enzymes, have aroused
much attention as the candidate in diverse fields with the arbitrarily tunable features owing to …

Nanozymes: definition, activity, and mechanisms

M Zandieh, J Liu - Advanced materials, 2024 - Wiley Online Library
Abstract “Nanozyme” is used to describe various catalysts from immobilized inorganic metal
complexes, immobilized enzymes to inorganic nanoparticles. Here, the history of …

Edge‐Site Engineering of Defective Fe–N4 Nanozymes with Boosted Catalase‐Like Performance for Retinal Vasculopathies

R Zhang, B Xue, Y Tao, H Zhao, Z Zhang… - Advanced …, 2022 - Wiley Online Library
Extensive efforts are devoted to refining metal sites for optimizing the catalytic performance
of single‐atom nanozymes (SANzymes), while the contribution of the defect environment of …

Dimensionality engineering of single-atom nanozyme for efficient peroxidase-mimicking

G Li, H Liu, T Hu, F Pu, J Ren, X Qu - Journal of the American …, 2023 - ACS Publications
In nature, enzymatic reactions occur in well-functioning catalytic pockets, where substrates
bind and react by properly arranging the catalytic sites and amino acids in a three …

Coordination-driven self-assembly strategy-activated Cu single-atom nanozymes for catalytic tumor-specific therapy

J Zhou, D Xu, G Tian, Q He, X Zhang… - Journal of the …, 2023 - ACS Publications
How to optimize the enzyme-like catalytic activity of nanozymes to improve their applicability
has become a great challenge. Herein, we present an l-cysteine (l-Cys) coordination-driven …

Tumor‐microenvironment‐responsive cascade reactions by a cobalt‐single‐atom nanozyme for synergistic nanocatalytic chemotherapy

S Cai, J Liu, J Ding, Z Fu, H Li, Y Xiong… - Angewandte …, 2022 - Wiley Online Library
Nanocatalytic therapy, involving the nanozyme‐triggered production of reactive oxygen
species (ROS) in the tumor microenvironment (TME), has demonstrated potential in tumor …

Atomically site synergistic effects of dual-atom nanozyme enhances peroxidase-like properties

R Zeng, Y Li, X Hu, W Wang, Y Li, H Gong, J Xu… - Nano Letters, 2023 - ACS Publications
Pursuing effective and generalized strategies for modulating the electronic structures of
atomically dispersed nanozymes with remarkable catalytic performance is exceptionally …

Matching the kinetics of natural enzymes with a single-atom iron nanozyme

S Ji, B Jiang, H Hao, Y Chen, J Dong, Y Mao… - Nature Catalysis, 2021 - nature.com
Developing artificial enzymes with the excellent catalytic performance of natural enzymes
has been a long-standing goal for chemists. Single-atom catalysts with well-defined atomic …

Tailoring acidic oxygen reduction selectivity on single-atom catalysts via modification of first and second coordination spheres

C Tang, L Chen, H Li, L Li, Y Jiao… - Journal of the …, 2021 - ACS Publications
Product selectivity in multielectron electrocatalytic reactions is crucial to energy conversion
efficiency and chemical production. However, a present practical drawback is the limited …