Inorganic polyphosphate (Poly P) is a polymer of tens to hundreds of phosphate residues
linked by “high-energy” phosphoanhydride bonds as in ATP. Found in abundance in all cells …

Recent work has shown that acidocalcisomes, which are electron-dense acidic organelles
rich in calcium and polyphosphate, are the only organelles that have been conserved during …

Inorganic polyphosphate (polyP) has been identified and measured in human platelets.
Millimolar levels (in terms of P i residues) of short chain polyP were found. The presence of …

Apicomplexan parasites, including Toxoplasma gondii, apically attach to their host cells
before invasion. Recent studies have implicated the contents of micronemes, which are …

Establishment of infection by Trypanosoma cruzi, the agent of Chagas' disease, depends on
a series of events involving interactions of diverse parasite molecules with host components …

Apicomplexan parasites have complex life cycles, frequently split between different hosts
and reliant on rapid responses as the parasites react to changing environmental conditions …

Acidocalcisomes are acidic organelles containing calcium and a high concentration of
phosphorus in the form of pyrophosphate (PPi) and polyphosphate (poly P). Organelles with …

Leishmania donovani is the causing agent of visceral leishmaniasis, a common infection
that affects millions of people from the most underdeveloped countries. Miltefosine is the …

Leishmania and Trypanosoma belong to the Trypanosomatidae family and cause important
human infections such as leishmaniasis, Chagas disease, and sleeping sickness …

Inorganic polyphosphates (polyPs) and inositol pyrophosphates (PP‐InsPs) form important
stores of inorganic phosphate and can act as energy metabolites and signaling molecules …