Non-spherical micro-and nanoparticles for drug delivery: Progress over 15 years
Shape of particulate drug carries has been identified as a key parameter in determining their
biological outcome. In this review, we analyze the field of particle shape as it shifts from …
biological outcome. In this review, we analyze the field of particle shape as it shifts from …
Medulloblastoma targeted therapy: From signaling pathways heterogeneity and current treatment dilemma to the recent advances in development of therapeutic …
Medulloblastoma (MB) is a major pediatric malignant brain tumor that arises in the
cerebellum. MB tumors exhibit highly heterogeneous driven by diverse genetic alterations …
cerebellum. MB tumors exhibit highly heterogeneous driven by diverse genetic alterations …
Polymersomes as the Next Attractive Generation of Drug Delivery Systems: Definition, Synthesis and Applications
M Fonseca, I Jarak, F Victor, C Domingues, F Veiga… - Materials, 2024 - mdpi.com
Polymersomes are artificial nanoparticles formed by the self-assembly process of
amphiphilic block copolymers composed of hydrophobic and hydrophilic blocks. They can …
amphiphilic block copolymers composed of hydrophobic and hydrophilic blocks. They can …
Intelligent design of polymersomes for antibacterial and anticancer applications
T Wang, J Qin, J Cheng, C Li… - Wiley Interdisciplinary …, 2022 - Wiley Online Library
Polymersomes (or polymer vesicles) have attracted much attention for biomedical
applications in recent years because their lumen can be used for drug delivery and their …
applications in recent years because their lumen can be used for drug delivery and their …
[HTML][HTML] Clusters of polymersomes and Janus nanoparticles hierarchically self-organized and controlled by DNA hybridization
The combination of “hard”, structurally well-defined particles with “soft”, functional
compartments bears great potential to produce structurally intricate hybrid nanomaterials …
compartments bears great potential to produce structurally intricate hybrid nanomaterials …
Peptide ligands on the PEGylated nanoparticle surface and human serum composition are key factors for the interaction between immune cells and nanoparticles
AG Pershina, AM Demin, NA Perekucha… - Colloids and Surfaces B …, 2023 - Elsevier
The architecture of a nanoparticles' surface formed due to a modification with a ligand and
protein corona formation in biofluids is critical for interactions with cells in vivo. Here we …
protein corona formation in biofluids is critical for interactions with cells in vivo. Here we …
Synthetic Cells Revisited: Artificial Cells Construction Using Polymeric Building Blocks
The exponential growth of research on artificial cells and organelles underscores their
potential as tools to advance the understanding of fundamental biological processes. The …
potential as tools to advance the understanding of fundamental biological processes. The …
Nonspherical nanocapsules as long-circulating drug delivery systems
Y Xiao, A Tan, AW Jackson, BJ Boyd - Chemistry of Materials, 2022 - ACS Publications
Polymeric nanocapsules have been studied as drug delivery carriers for a great variety of
drugs for more than 30 years. In particular, nonspherical polymeric nanoparticles with solid …
drugs for more than 30 years. In particular, nonspherical polymeric nanoparticles with solid …
Convoluted micellar morphological transitions driven by tailorable mesogenic ordering effect from discotic mesogen-containing block copolymer
H Yang, Y Luo, B Jin, S Chi, X Li - Nature Communications, 2024 - nature.com
Solution-state self-assemblies of block copolymers to form nanostructures are tremendously
attractive for their tailorable morphologies and functionalities. While incorporating moieties …
attractive for their tailorable morphologies and functionalities. While incorporating moieties …
Combining nanoparticle shape modulation and polymersome technology in drug delivery
This paper highlights the potential benefits of using self-assembled polymeric nanoparticles
of various shapes to enhance drug uptake. First, we highlight the growth and development of …
of various shapes to enhance drug uptake. First, we highlight the growth and development of …