Seven types of pleiotropy Page 1 Seven types of pleiotropy JONATHAN HODGKIN* MRC
Laboratory of Molecular Biology, Cambridge, United Kingdom ABSTRACT Pleiotropy, a …

▪ Abstract Proteins of the kinesin superfamily utilize a conserved catalytic motor domain to
generate movements in a wide variety of cellular processes. In this review, we discuss the …

A PRODUCT encoded at the claret locus in Drosophila is needed for normal chromosome
segregation in meiosis in females and in early mitotic divisions of the embryo1, 2. The …

During the formation of the metaphase spindle in animal somatic cells, kinetochore
microtubule bundles (K fibers) are often disconnected from centrosomes, because they are …

The Drosophila ncd gene is required for chromosome segregation during female meiosis.
Previous analyses suggested that the ncd gene encoded a protein with sequence similarity …

We have used time-lapse laser scanning confocal microscopy to directly examine
microtubule reorganization during meiotic spindle assembly in living Drosophila oocytes …

CONTRARY to the traditional view that microtubules pull chromosomes polewards during
the anaphase stage of meiotic and mitotic cell divisions, new evidence suggests that the …

The nod gene is required for the distributive segregation of nonexchange chromosomes
during meiosis in D. meianogaster. Loss-of-function nod mutations cause nondisjunction …

The Drosophila microtubule motor protein, nonclaret disjunctional (ned), is required for
proper chromosome distribution in meiosis and mitosis. We have examined the meiotic and …

Mature oocytes of Drosophila are arrested in metaphase of meiosis I. Upon activation by
ovulation or fertilization, oocytes undergo a series of rapid changes that have not been …