Characterizing the pattern of anomalies in congenital Zika syndrome for pediatric clinicians

CA Moore, JE Staples, WB Dobyns, A Pessoa… - JAMA …, 2017 - jamanetwork.com
Importance Zika virus infection can be prenatally passed from a pregnant woman to her
fetus. There is sufficient evidence to conclude that intrauterine Zika virus infection is a cause …

[HTML][HTML] The emergence of Zika virus and its new clinical syndromes

TC Pierson, MS Diamond - Nature, 2018 - nature.com
Zika virus (ZIKV) is a mosquito-transmitted flavivirus that has emerged as a global health
threat because of its potential to generate explosive epidemics and ability to cause …

Delayed childhood neurodevelopment and neurosensory alterations in the second year of life in a prospective cohort of ZIKV-exposed children

K Nielsen-Saines, P Brasil, T Kerin, Z Vasconcelos… - Nature medicine, 2019 - nature.com
We report neurodevelopmental outcomes in 216 infants followed since the time of PCR-
confirmed maternal Zika virus (ZIKV) infection in pregnancy during the Rio de Janeiro …

[HTML][HTML] Congenital Zika syndrome: A systematic review

DA Freitas, R Souza-Santos, LMA Carvalho… - PLoS …, 2020 - journals.plos.org
Background The signs and symptoms of Zika virus infection are usually mild and self-limited.
However, the disease has been linked to neurological complications such as Guillain-Barré …

[HTML][HTML] Description of 13 infants born during October 2015–January 2016 with congenital Zika virus infection without microcephaly at birth—Brazil

V Van der Linden - MMWR. Morbidity and mortality weekly report, 2016 - cdc.gov
Congenital Zika virus infection can cause microcephaly and severe brain abnormalities. As
more information about the associated clinical syndrome becomes available, the phenotype …

Birth defects among fetuses and infants of US women with evidence of possible Zika virus infection during pregnancy

MA Honein, AL Dawson, EE Petersen, AM Jones… - Jama, 2017 - jamanetwork.com
Importance Understanding the risk of birth defects associated with Zika virus infection during
pregnancy may help guide communication, prevention, and planning efforts. In the absence …

The phenotypic spectrum of congenital Zika syndrome

M Del Campo, IML Feitosa, EM Ribeiro… - American Journal of …, 2017 - Wiley Online Library
In October 2015, Zika virus (ZIKV) outbreak the Brazilian Ministry of Health (MoH). In
response, the Brazilian Society of Medical Genetics established a task force (SBGM‐ZETF) …

[HTML][HTML] Zika-virus-encoded NS2A disrupts mammalian cortical neurogenesis by degrading adherens junction proteins

KJ Yoon, G Song, X Qian, J Pan, D Xu, HS Rho… - Cell stem cell, 2017 - cell.com
Zika virus (ZIKV) directly infects neural progenitors and impairs their proliferation. How ZIKV
interacts with the host molecular machinery to impact neurogenesis in vivo is not well …

Congenital Zika virus infection as a silent pathology with loss of neurogenic output in the fetal brain

KM Adams Waldorf, BR Nelson… - Nature medicine, 2018 - nature.com
Zika virus (ZIKV) is a flavivirus with teratogenic effects on fetal brain, but the spectrum of
ZIKV-induced brain injury is unknown, particularly when ultrasound imaging is normal. In a …

Motor abnormalities and epilepsy in infants and children with evidence of congenital Zika virus infection

A Pessoa, V van der Linden, M Yeargin-Allsopp… - …, 2018 - publications.aap.org
Initial reports of congenital Zika virus (ZIKV) infection focused on microcephaly at birth with
severe brain anomalies; the phenotype has broadened to include microcephaly that …