Chemodynamic therapy (CDT), a novel cancer therapeutic strategy defined as the treatment
using Fenton or Fenton‐like reaction to produce• OH in the tumor region, was first proposed …

Tumor microenvironment (TME) is a specialized ecosystem of host components, designed
by tumor cells for successful development and metastasis of tumor. With the advent of 3D …

Microenvironment-responsive drug delivery systems (DDSs) can achieve targeted drug
delivery, reduce drug side effects and improve drug efficacies. Among them, pH-responsive …

Background Despite advances in early detection and therapies, cancer is still one of the
most common causes of death worldwide. Since each tumor is unique, there is a need to …

Since the first connection between Fenton chemistry and biomedicine, numerous studies
have been presented in this field. Comprehensive presentation of the guidance from Fenton …

Contrary to Warburg's original thesis, accelerated aerobic glycolysis is not a primary,
permanent and universal consequence of dysfunctional or impaired mitochondria …

Accumulating evidence shows that cellular and acellular components in tumor
microenvironment (TME) can reprogram tumor initiation, growth, invasion, metastasis, and …

Immunotherapy holds the potential to induce durable responses, but only a minority of
patients currently respond. The etiologies of primary and secondary resistance to …

Background and Objectives: The tumor microenvironment has been widely implicated in
tumorigenesis because it harbors tumor cells that interact with surrounding cells through the …

Systemic chemotherapy remains the backbone of many cancer treatments. Due to its
untargeted nature and the severe side effects it can cause, numerous nanomedicine …