Evidence of ternary complex formation in Trypanosoma cruzi trans-sialidase catalysis

IA Oliveira, AS Gonçalves, JL Neves… - Journal of Biological …, 2014 - ASBMB
Trypanosoma cruzi trans-sialidase (TcTS) is a key target protein for Chagas disease
chemotherapy. In this study, we investigated the implications of active site flexibility on the …