Flux estimation analysis systematically characterizes the metabolic shifts of the central metabolism pathway in human cancer

G Yang, S Huang, K Hu, A Lu, J Yang… - Frontiers in …, 2023 - frontiersin.org
Introduction Glucose and glutamine are major carbon and energy sources that promote the
rapid proliferation of cancer cells. Metabolic shifts observed on cell lines or mouse models …

A method to identify high consensus predictions of single-cell metabolic flux

JMB Amiss, H Jabbari, J Lum - bioRxiv, 2024 - biorxiv.org
Altered metabolism is a key contributor to pathology in numerous disease states, including
cancer. These changes can occur within certain pathological cells, or within a population of …

The Enhanced Prediction of Single-cell Metabolism through Consensus Methods

JM Amiss - 2023 - dspace.library.uvic.ca
Motivation: Altered metabolism is a key contributor to pathology in multiple dis ease states.
In cancers, metabolic shifts are crucial to providing the tumor cells with the energy and …