Transmission-blocking drugs for malaria elimination
LM Birkholtz, P Alano, D Leroy - Trends in parasitology, 2022 - cell.com
Preventing human-to-mosquito transmission of malaria parasites provides possible
solutions to interrupt the malaria parasite life cycle for malaria elimination. The development …
solutions to interrupt the malaria parasite life cycle for malaria elimination. The development …
Plasmodium vivax: the potential obstacles it presents to malaria elimination and eradication
K Habtamu, B Petros, G Yan - Tropical Diseases, Travel Medicine and …, 2022 - Springer
Initiatives to eradicate malaria have a good impact on P. falciparum malaria worldwide. P.
vivax, however, still presents significant difficulties. This is due to its unique biological traits …
vivax, however, still presents significant difficulties. This is due to its unique biological traits …
Antimalarial Drug Strategies to Target Plasmodium Gametocytes
BA Munro, BJ McMorran - Parasitologia, 2022 - mdpi.com
Onward transmission of Plasmodium falciparum from humans to mosquitoes is dependent
upon a specialised transmission stage called the gametocyte. Despite its critical role in …
upon a specialised transmission stage called the gametocyte. Despite its critical role in …
Hypnozoite dynamics for Plasmodium vivax malaria: the epidemiological effects of radical cure
Malaria is a mosquito-borne disease with a devastating global impact. Plasmodium vivax is
a major cause of human malaria beyond sub-Saharan Africa. Relapsing infections, driven by …
a major cause of human malaria beyond sub-Saharan Africa. Relapsing infections, driven by …
Comparison of PvLAP5 and Pvs25 qRT-PCR assays for the detection of Plasmodium vivax gametocytes in field samples preserved at ambient temperature from …
N Obaldía, I Barahona, J Lasso, M Avila… - PLoS neglected …, 2022 - journals.plos.org
Background As the elimination of malaria in Mesoamerica progresses, detection of
Plasmodium vivax using light microscopy (LM) becomes more difficult. Highly sensitive …
Plasmodium vivax using light microscopy (LM) becomes more difficult. Highly sensitive …
Plasmodium falciparum and Plasmodium vivax Adjust Investment in Transmission in Response to Change in Transmission Intensity: A Review of the Current State of …
Malaria parasites can adjust the proportion of parasites that develop into gametocytes, and
thus the probability for human-to-vector transmission, through changes in the gametocyte …
thus the probability for human-to-vector transmission, through changes in the gametocyte …
Update on pathogenesis, management, and control of Plasmodium vivax
N Khan, JP Daily - Current opinion in infectious diseases, 2022 - journals.lww.com
P. vivax is a significant global health problem. There have been recent developments in
understanding the complexity of P. vivax biology and optimization of antimalarial therapy …
understanding the complexity of P. vivax biology and optimization of antimalarial therapy …
qPCR in a suitcase for rapid Plasmodium falciparum and Plasmodium vivax surveillance in Ethiopia
Many Plasmodium spp. infections, both in clinical and asymptomatic patients, are below the
limit of detection of light microscopy or rapid diagnostic test (RDT). Molecular diagnosis by …
limit of detection of light microscopy or rapid diagnostic test (RDT). Molecular diagnosis by …
Plasmodium gametocyte carriage in humans and sporozoite rate in anopheline mosquitoes in Gondar zuria district, Northwest Ethiopia
A Minwuyelet, M Abiye, AJ Zeleke, S Getie - Plos one, 2024 - journals.plos.org
Although the overall burden of malaria is decreasing in Ethiopia, a recent report of an
unpredictable increased incidence may be related to the presence of community-wide …
unpredictable increased incidence may be related to the presence of community-wide …
Freedom from infection: enhancing decision-making for malaria elimination
Assessing elimination of malaria locally requires a surveillance system with high sensitivity
and specificity to detect its presence without ambiguity. Currently, the WHO standard criteria …
and specificity to detect its presence without ambiguity. Currently, the WHO standard criteria …