Introduction Obesity is a disorder characterized by a disproportionate increase in body
weight in relation to height, mainly due to the accumulation of fat, and is considered a …

Phosphatidylcholines (PCs) are the major components of biological membranes in animals
and are a class of phospholipids that incorporate choline as a headgroup …

Background Developing an understanding of the biochemistry of aging in both sexes is
critical for managing disease throughout the lifespan. Lipidomic associations with age and …

Expanding metabolome coverage to include complex lipids and polar metabolites is
essential in the generation of well-founded hypotheses in biological assays. Traditionally …

Modulation of the gut microbiota may help in treating obesity by improving host metabolic
health. We aimed to evaluate the effects of probiotics or symbiotics on body weight and …

Obesity rates among children are growing rapidly worldwide, placing massive pressure on
healthcare systems. Untargeted metabolomics can expand our understanding of the …

Brown and beige fat are specialized for energy expenditure by dissipating energy from
glucose and fatty acid oxidation as heat. While glucose and fatty acid metabolism have been …

Aim Diabetic nephropathy (DN) is one of the worst complications of diabetes. Despite a
growing number of DN metabolite profiling studies, most studies are suffering from …

Obesity plays an important role in the development of insulin resistance and diabetes, but
the molecular mechanism that links obesity and diabetes is still not completely understood …

Obesity is a global pandemic, but there is yet no effective measure to control it. Recent
metabolomics studies have identified a signature of altered amino acid profiles to be …