[HTML][HTML] Melanin and melanin-functionalized nanoparticles as promising tools in cancer research—a review

I Marcovici, D Coricovac, I Pinzaru, IG Macasoi… - Cancers, 2022 - mdpi.com
Simple Summary Although a notable evolution was recorded in the field of cancer, both in
terms of therapeutic options and diagnostic tools, with nanotechnology contributing …

[HTML][HTML] Developments in 177Lu-based radiopharmaceutical therapy and dosimetry

SC George, EJJ Samuel - Frontiers in Chemistry, 2023 - frontiersin.org
177Lu is a radioisotope that has become increasingly popular as a therapeutic agent for
treating various conditions, including neuroendocrine tumors and metastatic prostate …

[HTML][HTML] Clinical advances and perspectives in targeted radionuclide therapy

N Lepareur, B Ramée, M Mougin-Degraef… - Pharmaceutics, 2023 - mdpi.com
Targeted radionuclide therapy has become increasingly prominent as a nuclear medicine
subspecialty. For many decades, treatment with radionuclides has been mainly restricted to …

[HTML][HTML] Radiomics and Artificial Intelligence in Radiotheranostics: a review of applications for Radioligands Targeting somatostatin receptors and prostate-specific …

E Yazdani, P Geramifar, N Karamzade-Ziarati… - Diagnostics, 2024 - mdpi.com
Radiotheranostics refers to the pairing of radioactive imaging biomarkers with radioactive
therapeutic compounds that deliver ionizing radiation. Given the introduction of very …

Why bother with alpha particles?

AP King, FI Lin, FE Escorcia - European Journal of Nuclear Medicine and …, 2021 - Springer
The approval of 223 RaCl 2 for cancer therapy in 2013 has heralded a resurgence of
interest in the development of α-particle emitting radiopharmaceuticals. In the last decade …

An international study of factors affecting variability of dosimetry calculations, part 1: design and early results of the SNMMI dosimetry challenge

C Uribe, A Peterson, B Van, R Fedrigo… - Journal of Nuclear …, 2021 - Soc Nuclear Med
In this work, we present details and initial results from a 177 Lu dosimetry challenge that has
been designed to collect data from the global nuclear medicine community aiming at …

Training end-to-end unrolled iterative neural networks for SPECT image reconstruction

Z Li, YK Dewaraja, JA Fessler - IEEE transactions on radiation …, 2023 - ieeexplore.ieee.org
Training end-to-end unrolled iterative neural networks for single-photon emission
computerized tomography (SPECT) image reconstruction requires a memory-efficient …

Targeted Alpha Therapy of Glioma Using 211At-Labeled Heterodimeric Peptide Targeting Both VEGFR and Integrins

W Liu, H Ma, R Liang, X Chen, H Li, T Lan… - Molecular …, 2022 - ACS Publications
Targeted radionuclide therapy based on α-emitters plays an increasingly important role in
cancer treatment. In this study, we proposed to apply a heterodimeric peptide (iRGD-C6-lys …

[HTML][HTML] Roadmap for precision preclinical x-ray radiation studies

F Verhaegen, KT Butterworth… - Physics in Medicine …, 2023 - iopscience.iop.org
This Roadmap paper covers the field of precision preclinical x-ray radiation studies in
animal models. It is mostly focused on models for cancer and normal tissue response to …

[HTML][HTML] Localized radiotherapy of solid tumors using radiopharmaceutical loaded implantable system: insights from a mathematical model

A Piranfar, M Souri, A Rahmim, M Soltani - Frontiers in Oncology, 2024 - frontiersin.org
Introduction Computational models yield valuable insights into biological interactions not
fully elucidated by experimental approaches. This study investigates an innovative …