There are seven relaxin family peptides that are all structurally related to insulin. Relaxin has
many roles in female and male reproduction, as a neuropeptide in the central nervous …

The bed nucleus of the stria terminalis (BNST) is widely acknowledged as a brain structure
that regulates stress and anxiety states, as well as aversive and appetitive behaviours. The …

Relaxin, insulin-like peptide 3 (INSL3), relaxin-3, and INSL5 are the cognate ligands for the
relaxin family peptide (RXFP) receptors 1–4, respectively. RXFP1 activates pleiotropic …

Abstract Relaxin‐3 (RLN3) and its native receptor, relaxin family peptide 3 receptor
(RXFP3), constitute a newly identified neuropeptide system enriched in mammalian brain …

Hippocampal theta rhythm is thought to underlie learning and memory, and it is well
established that “pacemaker” neurons in medial septum (MS) modulate theta activity. Recent …

Relaxin‐3 is a member of a superfamily of structurally‐related peptides that includes relaxin
and insulin‐like peptide hormones. Soon after the discovery of the relaxin‐3 gene, relaxin‐3 …

The relaxin-3 gene was identified in 2001 by searching the human genome database for
homologues of the relaxin hormone, and was subsequently discovered to encode a highly …

The identification in the 1950s of insulin, an essential carbohydrate regulatory hormone, as
consisting of not one but two peptide chains linked by three disulfide bonds in a distinctive …

The relaxin family peptides, although structurally closely related to insulin, act on a group of
four G protein‐coupled receptors now known as Relaxin Family Peptide (RXFP) Receptors …

This study investigated sex‐specific effects of repeated stress and food restriction on food
intake, body weight, corticosterone plasma levels and expression of corticotropin‐releasing …