New insights into the mechanisms of diabetic complications: role of lipids and lipid metabolism

S Eid, KM Sas, SF Abcouwer, EL Feldman, TW Gardner… - Diabetologia, 2019 - Springer
Diabetes adversely affects multiple organs, including the kidney, eye and nerve, leading to
diabetic kidney disease, diabetic retinopathy and diabetic neuropathy, respectively. In both …

[HTML][HTML] Benefits of supplementation with microbial omega-3 fatty acids on human health and the current market scenario for fish-free omega-3 fatty acid

D Karageorgou, U Rova, P Christakopoulos… - Trends in Food Science …, 2023 - Elsevier
Background Growing evidence points to a link between specific fatty acids ingested through
the diet and human health. Chain length, saturation degree, and position of double bonds in …

The role of diet, micronutrients and the gut microbiota in age-related macular degeneration: new perspectives from the gut–retina axis

E Rinninella, MC Mele, N Merendino, M Cintoni… - Nutrients, 2018 - mdpi.com
Age-related macular degeneration (AMD) is a complex multifactorial disease and the
primary cause of legal and irreversible blindness among individuals aged≥ 65 years in …

Oxidative stress as the main target in diabetic retinopathy pathophysiology

OM Cecilia, CG José Alberto, NP José… - Journal of diabetes …, 2019 - Wiley Online Library
Diabetic retinopathy (DR) is one of the most common complications of diabetes mellitus
(DM) causing vision impairment even at young ages. There are numerous mechanisms …

[WITHDRAWN] retinal vasculature in development and diseases

Y Sun, LEH Smith - Annual review of vision science, 2018 - annualreviews.org
This article was withdrawn on October 15, 2020, at the request of the journal editors, with
agreement from the authors, owing to a substantial amount of unattributed or improperly …

Retinal energy demands control vascular supply of the retina in development and disease: The role of neuronal lipid and glucose metabolism

JS Joyal, ML Gantner, LEH Smith - Progress in retinal and eye research, 2018 - Elsevier
Neuronal energy demands are met by a tightly coupled and adaptive vascular network that
supplies nutrients and oxygen. The retina is one of the highest energy-consuming organs …

Emerging roles of dyslipidemia and hyperglycemia in diabetic retinopathy: molecular mechanisms and clinical perspectives

H Rao, JA Jalali, TP Johnston, P Koulen - Frontiers in endocrinology, 2021 - frontiersin.org
Diabetic retinopathy (DR) is a significant cause of vision loss and a research subject that is
constantly being explored for new mechanisms of damage and potential therapeutic options …

Dyslipidemia in retinal metabolic disorders

Z Fu, CT Chen, G Cagnone, E Heckel… - EMBO Molecular …, 2019 - embopress.org
The light‐sensitive photoreceptors in the retina are extremely metabolically demanding and
have the highest density of mitochondria of any cell in the body. Both physiological and …

Eicosanoids and oxidative stress in diabetic retinopathy

MH Wang, G Hsiao, M Al-Shabrawey - Antioxidants, 2020 - mdpi.com
Oxidative stress is an important factor to cause the pathogenesis of diabetic retinopathy (DR)
because the retina has high vascularization and long-time light exposition. Cyclooxygenase …

Adjuvant therapies in diabetic retinopathy as an early approach to delay its progression: the importance of oxidative stress and inflammation

RR Robles-Rivera… - Oxidative medicine …, 2020 - Wiley Online Library
Diabetes mellitus (DM) is a progressive disease induced by a sustained state of chronic
hyperglycemia that can lead to several complications targeting highly metabolic cells …