Redesign of protein nanocages: the way from 0D, 1D, 2D to 3D assembly
Compartmentalization is a hallmark of living systems. Through compartmentalization,
ubiquitous protein nanocages such as viral capsids, ferritin, small heat shock proteins, and …
ubiquitous protein nanocages such as viral capsids, ferritin, small heat shock proteins, and …
Ferritin-based drug delivery systems: Hybrid nanocarriers for vascular immunotargeting
M Khoshnejad, H Parhiz, VV Shuvaev… - Journal of Controlled …, 2018 - Elsevier
Ferritin subunits of heavy and light polypeptide chains self-assemble into a spherical
nanocage that serves as a natural transport vehicle for metals but can include diverse …
nanocage that serves as a natural transport vehicle for metals but can include diverse …
Enzyme hydration determines resistance in organic cosolvents
Biocatalysis in organic solvents (OSs) has found various important applications, particularly
in organic synthesis and for the production of pharmaceuticals, flavors, and fragrances …
in organic synthesis and for the production of pharmaceuticals, flavors, and fragrances …
Spatially patterned, porous protein crystals as multifunctional materials
K Han, Z Zhang, FA Tezcan - Journal of the American Chemical …, 2023 - ACS Publications
While the primary use of protein crystals has historically been in crystallographic structure
determination, they have recently emerged as promising materials with many advantageous …
determination, they have recently emerged as promising materials with many advantageous …
How to engineer organic solvent resistant enzymes: Insights from combined molecular dynamics and directed evolution study
Expanding synthetic capabilities to routinely employ enzymes in organic solvents (OSs) is a
dream for protein engineers and synthetic chemists. Despite significant advances in the field …
dream for protein engineers and synthetic chemists. Despite significant advances in the field …
Enzyme Hydration: How to Retain Resistance in Ionic Liquids
Application of ionic liquids (ILs) as media in biocatalysis has enormous potential for
synthesizing valuable compounds and bulk products in pharmaceuticals and bioenergy due …
synthesizing valuable compounds and bulk products in pharmaceuticals and bioenergy due …
Encapsulation of gold nanoparticles into redesigned ferritin nanocages for the assembly of binary superlattices composed of fluorophores and gold nanoparticles
M Lach, C Strelow, A Meyer, A Mews… - ACS Applied Materials & …, 2022 - ACS Publications
Nanomaterials with a defined composition and structure can be synthesized by exploiting
natural templates or biomolecular matrices. In the present work, we use protein nanocages …
natural templates or biomolecular matrices. In the present work, we use protein nanocages …
Bacterioferritin nanocage: Structure, biological function, catalytic mechanism, self-assembly and potential applications
M Guo, M Gao, J Liu, N Xu, H Wang - Biotechnology Advances, 2022 - Elsevier
Bacterioferritin (Bfr) is a subfamily of ferritin protein family. Bfrs are composed of 24 identical
subunits and self-assemble into 4‐3-2-fold symmetric cage-like structure with the …
subunits and self-assemble into 4‐3-2-fold symmetric cage-like structure with the …
Spatially controlled assembly of affinity ligand and enzyme cargo enables targeting ferritin nanocarriers to caveolae
VV Shuvaev, M Khoshnejad, KW Pulsipher… - Biomaterials, 2018 - Elsevier
One of the goals of nanomedicine is targeted delivery of therapeutic enzymes to the sub-
cellular compartments where their action is needed. Endothelial caveolae-derived …
cellular compartments where their action is needed. Endothelial caveolae-derived …
Virus-like particles and nanoparticles for vaccine development against HCMV
M Perotti, L Perez - Viruses, 2019 - mdpi.com
Human cytomegalovirus (HCMV) infects more than 70% of the human population worldwide.
HCMV is responsible for high morbidity and mortality in immunocompromised patients and …
HCMV is responsible for high morbidity and mortality in immunocompromised patients and …