Redesign of protein nanocages: the way from 0D, 1D, 2D to 3D assembly

C Lv, X Zhang, Y Liu, T Zhang, H Chen… - Chemical Society …, 2021 - pubs.rsc.org
Compartmentalization is a hallmark of living systems. Through compartmentalization,
ubiquitous protein nanocages such as viral capsids, ferritin, small heat shock proteins, and …

Ferritin-based drug delivery systems: Hybrid nanocarriers for vascular immunotargeting

M Khoshnejad, H Parhiz, VV Shuvaev… - Journal of Controlled …, 2018 - Elsevier
Ferritin subunits of heavy and light polypeptide chains self-assemble into a spherical
nanocage that serves as a natural transport vehicle for metals but can include diverse …

Enzyme hydration determines resistance in organic cosolvents

H Cui, L Zhang, L Eltoukhy, Q Jiang, SK Korkunç… - ACS …, 2020 - ACS Publications
Biocatalysis in organic solvents (OSs) has found various important applications, particularly
in organic synthesis and for the production of pharmaceuticals, flavors, and fragrances …

Spatially patterned, porous protein crystals as multifunctional materials

K Han, Z Zhang, FA Tezcan - Journal of the American Chemical …, 2023 - ACS Publications
While the primary use of protein crystals has historically been in crystallographic structure
determination, they have recently emerged as promising materials with many advantageous …

How to engineer organic solvent resistant enzymes: Insights from combined molecular dynamics and directed evolution study

H Cui, THJ Stadtmüller, Q Jiang, KE Jaeger… - …, 2020 - Wiley Online Library
Expanding synthetic capabilities to routinely employ enzymes in organic solvents (OSs) is a
dream for protein engineers and synthetic chemists. Despite significant advances in the field …

Enzyme Hydration: How to Retain Resistance in Ionic Liquids

H Cui, L Zhang, CB Yildiz, L Eltoukhy… - ACS Sustainable …, 2022 - ACS Publications
Application of ionic liquids (ILs) as media in biocatalysis has enormous potential for
synthesizing valuable compounds and bulk products in pharmaceuticals and bioenergy due …

Encapsulation of gold nanoparticles into redesigned ferritin nanocages for the assembly of binary superlattices composed of fluorophores and gold nanoparticles

M Lach, C Strelow, A Meyer, A Mews… - ACS Applied Materials & …, 2022 - ACS Publications
Nanomaterials with a defined composition and structure can be synthesized by exploiting
natural templates or biomolecular matrices. In the present work, we use protein nanocages …

Bacterioferritin nanocage: Structure, biological function, catalytic mechanism, self-assembly and potential applications

M Guo, M Gao, J Liu, N Xu, H Wang - Biotechnology Advances, 2022 - Elsevier
Bacterioferritin (Bfr) is a subfamily of ferritin protein family. Bfrs are composed of 24 identical
subunits and self-assemble into 4‐3-2-fold symmetric cage-like structure with the …

Spatially controlled assembly of affinity ligand and enzyme cargo enables targeting ferritin nanocarriers to caveolae

VV Shuvaev, M Khoshnejad, KW Pulsipher… - Biomaterials, 2018 - Elsevier
One of the goals of nanomedicine is targeted delivery of therapeutic enzymes to the sub-
cellular compartments where their action is needed. Endothelial caveolae-derived …

Virus-like particles and nanoparticles for vaccine development against HCMV

M Perotti, L Perez - Viruses, 2019 - mdpi.com
Human cytomegalovirus (HCMV) infects more than 70% of the human population worldwide.
HCMV is responsible for high morbidity and mortality in immunocompromised patients and …