Background Non-alcoholic fatty liver disease (NAFLD) is characterized by hepatic steatosis
in over 5% of the parenchyma in the absence of excessive alcohol consumption. It is more …

Depression has repeatedly been linked to subclinical hypothyroidism, and thyroid hormones
have successfully been used to augment antidepressant treatment. By contrast, the extent of …

Bipolar disorder is heterogeneous in phenomenology, illness trajectory, and response to
treatment. Despite evidence for the efficacy of multimodality interventions, the majority of …

Large-scale genomic and transcriptomic initiatives offer unprecedented insight into complex
traits, but clinical translation remains limited by variant-level associations without biological …

Background The DSM-5 mixed features specifier for mood disorders encourages renewed
interest in mixed states and led us to pool research findings regarding prevalence of mixed …

Background Autoimmune-mediated encephalitis is a disease that often encompasses
psychiatric symptoms as its first clinical manifestation's predominant and isolated …

Objective Our aim was to investigate evening chronotype, a proxy marker of circadian
system dysfunction, as a clinical subphenotype in bipolar disorder (BD). Methods In this …

Inflammation is hypothesized to be a key component of bipolar disorder (BP) development
and progression. However, findings linking BP prevalence and symptomology to immune …

Our review aims to delineate the psychiatric spectrum of autoantibody-associated
autoimmune encephalitis over time through its discoveries of antibodies. We searched in …

The onset of bipolar disorder (BD) occurs in childhood or adolescence in half of the patients.
Early stages of BD usually present depressive episodes, which makes it difficult to be …