New Trends and Future Opportunities in the Enzymatic Formation of C− C, C− N, and C− O bonds

JJ Sangster, JR Marshall, NJ Turner… - …, 2022 - Wiley Online Library
Organic chemistry provides society with fundamental products we use daily. Concerns about
the impact that the chemical industry has over the environment is propelling major changes …

Artemisinic acid: A promising molecule potentially suitable for the semi-synthesis of artemisinin

J Kong, Y Yang, W Wang, K Cheng, P Zhu - RSC advances, 2013 - pubs.rsc.org
Artemisinic acid, an amorphane sesquiterpene, is isolated from Artemisia annua L. Although
having less efficacy than artemisinin, artemisinic acid has a variety of pharmacological …

Six novel constitutive promoters for metabolic engineering of Aspergillus niger

M Blumhoff, MG Steiger, H Marx, D Mattanovich… - Applied microbiology …, 2013 - Springer
Genetic tools for the fine-tuning of gene expression levels are a prerequisite for rational
strain optimization through metabolic engineering. While Aspergillus niger is an industrially …

[PDF][PDF] Microbial production of isoprenoids

J Wong, L Rios-Solis, JD Keasling - Consequences of microbial …, 2017 - researchgate.net
Springer MRW: [AU:0, IDX:0] Page 1 Microbial Production of Isoprenoids J. Wong, L. Rios-Solis,
and JD Keasling Contents 1 Introduction …

Continuous production of fructooligosaccharides by recycling of the thermal-stable β-fructofuranosidase produced by Aspergillus niger

J Wang, J Zhang, L Wang, H Liu, N Li, H Zhou… - Biotechnology …, 2021 - Springer
Objective To achieve continuous production of fructooligosaccharides (FOS) by recycling of
the mycelial cells containing the thermal-stable β-fructofuranosidase in Aspergillus niger …

[HTML][HTML] Functional Expression of an Orchid Fragrance Gene in Lactococcus lactis

AAL Song, JO Abdullah, MP Abdullah… - International Journal of …, 2012 - mdpi.com
Vanda Mimi Palmer (VMP), an orchid hybrid of Vanda tesselata and Vanda Tan Chay Yan is
a highly scented tropical orchid which blooms all year round. Previous studies revealed that …

Metabolic engineering of plants for artemisinin synthesis

M Farhi, M Kozin, S Duchin… - Biotechnology and genetic …, 2013 - Taylor & Francis
Artemisinin, a natural compound from Artemisia annua, is highly effective in treating drug-
resistant malaria. Because chemical synthesis of this natural terpenoid is not economically …

Side products of recombinant amorpha-4, 11-diene synthase and their effect on microbial artemisinin production

JQ Huang, DM Li, X Tian, JL Lin, L Yang… - Journal of Agricultural …, 2021 - ACS Publications
Amorpha-4, 11-diene synthase (ADS) is the first committed enzyme in the biosynthesis of
artemisinin. Artemisinin production by biobased fermentation is considered a reliable …

Engineering Aspergillus nidulans for heterologous ent-kaurene and gamma-terpinene production

K Bromann, M Toivari, K Viljanen, L Ruohonen… - Applied microbiology …, 2016 - Springer
Terpenes are a large and varied group of natural products with a wide array of bioactivities
and applications. The chemical production of industrially relevant terpenes can be …

Effect of gpd box copy numbers in the gpdA promoter of Aspergillus nidulans on its transcription efficiency in Aspergillus niger

H Zhang, J Yan, H Zhang, T Liu, Y Xu… - FEMS microbiology …, 2018 - academic.oup.com
In this study, we characterised PgpdA, PgpdA2B, PgpdA3B and PgpdA4B promoters,
containing 1–4 copies of gpd box by modifying the gpdA promoter, and constructed pSZHGX …