Vulvar lichen sclerosus from pathophysiology to therapeutic approaches: evidence and prospects

M Corazza, N Schettini, P Zedde, A Borghi - Biomedicines, 2021 - mdpi.com
Vulvar lichen sclerosus (VLS) is a chronic, distressing, inflammatory disease with an
enormous impact on quality of life. Treatment goals are relieving symptoms, reversing signs …

Pathology and treatment of psoriasis using nanoformulations

D Thirumal, RK Sindhu, S Goyal, A Sehgal, A Kumar… - Biomedicines, 2023 - mdpi.com
Psoriasis (PSO) is an inflammatory skin condition that causes a variety of diseases and
significantly decreases the life characteristics of patients, and substantially diminishes …

A novel vehicle for the treatment of psoriasis

A Dattola, M Silvestri, L Bennardo… - Dermatologic …, 2020 - Wiley Online Library
This study evaluates the effectiveness of the topical use of an aerosol foam combination of
calcipotriol 50 μg/g plus betamethasone dipropionate 0.5 mg/g (Cal/BD foam, Enstilar®) in …

Epidemiological variations in the global burden of psoriasis, an analysis with trends from 1990 to 2017

C Peng, X Xu, W Chen, X Li, X Yi, Y Ding, N Yu… - Frontiers in …, 2021 - frontiersin.org
Background: Although there have been many epidemiological studies, research focusing on
psoriasis' health burden on a global scale is still lacking. Trends and variations in the global …

ROS-sensitive calcipotriol nano-micelles prepared by methoxypolyethylene glycol (mPEG)–modified polymer for the treatment of psoriasis

Y Hua, T Chang, K Jiang, J Wang, X Cui, M Cheng… - Drug Delivery, 2022 - Taylor & Francis
Oxidative stress due to excessive reactive oxygen species (ROS) production in the skin
microenvironment is one of the main mechanisms in psoriasis pathogenesis. A nano drug …

Preparation of calcipotriol emulsion using bacterial exopolysaccharides as emulsifier for percutaneous treatment of psoriasis vulgaris

B Song, R Song, M Cheng, H Chu, F Yan… - International Journal of …, 2019 - mdpi.com
An exopolysaccharides/calcipotriol (EPS/CPT) emulsion was prepared using bacterial EPS
as emulsifier, sunflower oil as an oil phase and CPT as the loaded drug, and the effect of this …

Therapeutic Effect of Calcipotriol Pickering Nanoemulsions Prepared by Exopolysaccharides Produced by Bacillus halotolerans FYS Strain on Psoriasis

Y Wang, H Li, F Dong, F Yan, M Cheng… - International Journal …, 2020 - Taylor & Francis
Purpose Many exopolysaccharides (EPS) have significant emulsifying activity. Some EPS
produced by the marine bacterial strain FYS have stronger emulsifying activity in the form of …

Calcipotriol/betamethasone dipropionate aerosol foam for the treatment of psoriasis vulgaris: a review of real-world evidence (RWE)

S Gerdes, M Velasco, JJ Wu, M Hubo… - Journal of …, 2021 - Taylor & Francis
Abstract Background Randomized controlled trials (RCTs) demonstrated the advantages of
an aerosol foam formulation of calcipotriol/betamethasone dipropionate (Cal/BD) in patients …

Safety of calcipotriene and betamethasone dipropionate foam for the treatment of psoriasis

V Amat-Samaranch, L Puig - Expert opinion on drug safety, 2020 - Taylor & Francis
Introduction: Psoriasis vulgaris is a chronic inflammatory skin disease characterized by well-
demarcated red and scaly plaques. Most patients have mild disease that is usually …

Calcipotriene/betamethasone dipropionate for the treatment of psoriasis vulgaris: an evidence-based review

NU Patel, K Felix, D Reimer… - Clinical, cosmetic and …, 2017 - Taylor & Francis
While topical medications remain the cornerstone of the psoriasis treatment paradigm, they
also come with the risk of multiple side effects. An alternative topical treatment option …