Ether lipids, such as plasmalogens, are peroxisome-derived glycerophospholipids in which
the hydrocarbon chain at the sn-1 position of the glycerol backbone is attached by an ether …

Systemic scleroderma (SSc) is one of the most complex systemic autoimmune diseases. It
targets the vasculature, connective tissue-producing cells (namely fibroblasts/myofibroblasts …

Peroxisomes are often dismissed as the cellular hoi polloi, relegated to cleaning up reactive
oxygen chemical debris discarded by other organelles. However, their functions extend far …

The nuclear receptor PPARγ is a ligand-activated transcription factor that plays an important
role in the control of gene expression linked to a variety of physiological processes. PPARγ …

CD36 (also known as scavenger receptor B2) is a multifunctional receptor that mediates the
binding and cellular uptake of long-chain fatty acids, oxidized lipids and phospholipids …

Rhododendron delavayi Franch. is globally famous as an ornamental plant. Its distribution in
southwest China covers several different habitats and environments. However, not much …

MicroRNAs (miRNAs) are a recently discovered class of endogenous, small, noncoding
RNAs that regulate about 30% of the encoding genes of the human genome. However, the …

Glycerol-based ether lipids including ether phospholipids form a specialized branch of lipids
that in mammals require peroxisomes for their biosynthesis. They are major components of …

Psoriasis is a common and chronic inflammatory skin disease that is complicated by gene–
environment interactions. Although genomic, transcriptomic, and proteomic analyses have …

Background Peroxisomes are single membrane-bound organelles named for their role in
hydrogen peroxide production and catabolism. However, their cellular functions extend well …