Mitochondrial involvement in psychiatric disorders
L Shao, MV Martin, SJ Watson, A Schatzberg… - Annals of …, 2008 - Taylor & Francis
Recent findings of mitochondrial abnormalities in brains from subjects with neurological
disorders have led to a renewed search for mitochondrial abnormalities in psychiatric …
disorders have led to a renewed search for mitochondrial abnormalities in psychiatric …
NOX4 activity is determined by mRNA levels and reveals a unique pattern of ROS generation
L Serrander, L Cartier, K Bedard, B Banfi… - Biochemical …, 2007 - portlandpress.com
NOX4 is an enigmatic member of the NOX (NADPH oxidase) family of ROS (reactive oxygen
species)-generating NADPH oxidases. NOX4 has a wide tissue distribution, but the …
species)-generating NADPH oxidases. NOX4 has a wide tissue distribution, but the …
The anticancer activity of the old neuroleptic phenothiazine-type drug thioridazine
G Spengler, Á Csonka, J Molnar, L Amaral - Anticancer research, 2016 - ar.iiarjournals.org
Thioridazine (TZ), an antipsychotic drug, renders multidrug-resistant (MDR) cancer cells
susceptible to cytotoxic agents to which they were initially resistant, has anti-prolilferative …
susceptible to cytotoxic agents to which they were initially resistant, has anti-prolilferative …
[HTML][HTML] Protective effect of Calendula officinalis extract against UVB-induced oxidative stress in skin: Evaluation of reduced glutathione levels and matrix …
YM Fonseca, CD Catini, FTMC Vicentini… - Journal of …, 2010 - Elsevier
BACKGROUND AND PURPOSE: Calendula officinalis flowers have long been employed
time in folk therapy, and more than 35 properties have been attributed to decoctions and …
time in folk therapy, and more than 35 properties have been attributed to decoctions and …
Thioridazine induces apoptosis by targeting the PI3K/Akt/mTOR pathway in cervical and endometrial cancer cells
S Kang, SM Dong, BR Kim, MS Park, B Trink, HJ Byun… - Apoptosis, 2012 - Springer
Abstract Recently, thioridazine (10-[2-(1-methyl-2-piperidyl) ethyl]-2-
methylthiophenothiazine), a well-known anti-psychotic agent was found to have anti-cancer …
methylthiophenothiazine), a well-known anti-psychotic agent was found to have anti-cancer …
Phenothiazines suppress proliferation and induce apoptosis in cultured leukemic cells without any influence on the viability of normal lymphocytes: Phenothiazines …
Z Zhelev, H Ohba, R Bakalova, V Hadjimitova… - Cancer chemotherapy …, 2004 - Springer
Purpose The purpose of the present study was to investigate the effects of phenothiazines
(at clinically relevant doses) on the viability and proliferation of leukemic cell lines and …
(at clinically relevant doses) on the viability and proliferation of leukemic cell lines and …
Spray drying of the soybean extract: Effects on chemical properties and antioxidant activity
SR Georgetti, R Casagrande, CRF Souza… - LWT-Food Science and …, 2008 - Elsevier
Recent findings that many human chronic diseases are associated with oxidative stresses
have instigated the search for dietary antioxidants. Isoflavones, a special phenolic group …
have instigated the search for dietary antioxidants. Isoflavones, a special phenolic group …
Assays of physical stability and antioxidant activity of a topical formulation added with different plant extracts
VM Di Mambro, MJV Fonseca - Journal of pharmaceutical and biomedical …, 2005 - Elsevier
In the present investigation the changes on physical stability (pH, viscosity, flow index and
tixotropy) of topical formulations were evaluated following inclusion of different plant extracts …
tixotropy) of topical formulations were evaluated following inclusion of different plant extracts …
[HTML][HTML] Role of mitochondria in cell apoptosis during hepatic ischemia-reperfusion injury and protective effect of ischemic postconditioning
K Sun, ZS Liu, Q Sun - World journal of gastroenterology: WJG, 2004 - ncbi.nlm.nih.gov
AIM: To investigate the role of mitochondria in cell apoptosis during hepatic ischemia-
reperfusion injury and protective effect of ischemic postconditioning (IPC). METHODS: A rat …
reperfusion injury and protective effect of ischemic postconditioning (IPC). METHODS: A rat …
Gold (III) porphyrin 1a induced apoptosis by mitochondrial death pathways related to reactive oxygen species
Y Wang, QY He, RWY Sun, CM Che, JF Chiu - Cancer research, 2005 - AACR
Apoptosis is a tightly controlled multistep mechanism of cell death, and mitochondria are
considered to play a central role in this process. Mitochondria initiate two distinct apoptosis …
considered to play a central role in this process. Mitochondria initiate two distinct apoptosis …